J 2018

Both ketamine and NBQX attenuate alcohol drinking in male Wistar rats

RUDÁ, Jana, Zuzana BABINSKÁ, Matej ĽUPTÁK, Bruk GETACHEW, Yousef TIZABI et. al.

Basic information

Original name

Both ketamine and NBQX attenuate alcohol drinking in male Wistar rats

Name in Czech

Ketamin i NBQX potlačují pití alkoholu u potkaních samců kmene Wistar

Authors

RUDÁ, Jana (203 Czech Republic, guarantor, belonging to the institution), Zuzana BABINSKÁ (703 Slovakia, belonging to the institution), Matej ĽUPTÁK (703 Slovakia, belonging to the institution), Bruk GETACHEW (840 United States of America) and Yousef TIZABI (840 United States of America)

Edition

Neuroscience Letters, Clare, Elsevier Ireland Ltd. 2018, 0304-3940

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.173

RIV identification code

RIV/00216224:14110/18:00102154

Organization unit

Faculty of Medicine

UT WoS

000426234700030

Keywords in English

Alcoholism; Alcohol use disorder; Glutamatergic receptors; NMDA receptor; AMPA receptor; Kainate receptor

Tags

International impact, Reviewed
Změněno: 9/2/2019 21:09, Soňa Böhmová

Abstract

V originále

Highlights: Acute low dose ketamine reduced alcohol intake but not alcohol-related behavioural effects. Acute low dose NBQX reduced alcohol intake but not alcohol-related behavioural effects. NMDA or AMPA/kainate receptor antagonists may have treatment potential in alcohol use disorder. These results suggest that selective antagonism of the NMDA or AMPA/kainate receptors may be of therapeutic potential in AUD.

Links

MUNI/A/1063/2016, interní kód MU
Name: Experimentální a translační farmakologický výzkum a vývoj
Investor: Masaryk University, Category A
MUNI/A/1132/2017, interní kód MU
Name: Behaviorální psychofarmakologie a farmakokinetika v preklinickém výzkumu léčiv
Investor: Masaryk University, Category A