RUDÁ, Jana, Zuzana BABINSKÁ, Matej ĽUPTÁK, Bruk GETACHEW and Yousef TIZABI. Both ketamine and NBQX attenuate alcohol drinking in male Wistar rats. Neuroscience Letters. Clare: Elsevier Ireland Ltd., 2018, vol. 666, FEB 14 2018, p. 175-180. ISSN 0304-3940. Available from: https://dx.doi.org/10.1016/j.neulet.2017.12.055.
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Basic information
Original name Both ketamine and NBQX attenuate alcohol drinking in male Wistar rats
Name in Czech Ketamin i NBQX potlačují pití alkoholu u potkaních samců kmene Wistar
Authors RUDÁ, Jana (203 Czech Republic, guarantor, belonging to the institution), Zuzana BABINSKÁ (703 Slovakia, belonging to the institution), Matej ĽUPTÁK (703 Slovakia, belonging to the institution), Bruk GETACHEW (840 United States of America) and Yousef TIZABI (840 United States of America).
Edition Neuroscience Letters, Clare, Elsevier Ireland Ltd. 2018, 0304-3940.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30103 Neurosciences
Country of publisher Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.173
RIV identification code RIV/00216224:14110/18:00102154
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.neulet.2017.12.055
UT WoS 000426234700030
Keywords in English Alcoholism; Alcohol use disorder; Glutamatergic receptors; NMDA receptor; AMPA receptor; Kainate receptor
Tags 14110516, EL OK, rivok
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 9/2/2019 21:09.
Abstract
Highlights: Acute low dose ketamine reduced alcohol intake but not alcohol-related behavioural effects. Acute low dose NBQX reduced alcohol intake but not alcohol-related behavioural effects. NMDA or AMPA/kainate receptor antagonists may have treatment potential in alcohol use disorder. These results suggest that selective antagonism of the NMDA or AMPA/kainate receptors may be of therapeutic potential in AUD.
Links
MUNI/A/1063/2016, interní kód MUName: Experimentální a translační farmakologický výzkum a vývoj
Investor: Masaryk University, Category A
MUNI/A/1132/2017, interní kód MUName: Behaviorální psychofarmakologie a farmakokinetika v preklinickém výzkumu léčiv
Investor: Masaryk University, Category A
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