Central venous catheter-related thrombosis in intensive care
patients - incidence and risk factors: A prospective
observational study

J 2017

Central venous catheter-related thrombosis in intensive care patients - incidence and risk factors: A prospective observational study

HRDÝ, Ondřej, Eva STRAŽEVSKÁ, Petr SUK, Robert VACH, Radim KARLÍK et. al.

Basic information

Original name

Central venous catheter-related thrombosis in intensive care patients - incidence and risk factors: A prospective observational study

Authors

HRDÝ, Ondřej (203 Czech Republic, guarantor, belonging to the institution), Eva STRAŽEVSKÁ (203 Czech Republic, belonging to the institution), Petr SUK (203 Czech Republic, belonging to the institution), Robert VACH (203 Czech Republic, belonging to the institution), Radim KARLÍK (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Igor SAS (203 Czech Republic, belonging to the institution) and Roman GÁL (203 Czech Republic, belonging to the institution)

Edition

Biomedical Papers, Olomouc: Palacky University, Olomouc, Palacky University, 2017, 1213-8118

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30223 Anaesthesiology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 1.087

RIV identification code

RIV/00216224:14110/17:00099082

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.5507/bp.2017.034

UT WoS

000418005200006

Keywords in English

central venous catheter; deep vein thrombosis; risk factors; critical care

Abstract

V originále

Background. One of the complications associated with central venous catheter (CVC) placement is catheter related deep vein thrombosis (CR-DVT). However a literature search revealed little evidence of this recognised complication. The primary aim of this study was to establish the incidence rate and risk factors for the development of CR-DVT in our critically ill adult patients. Methods. All critically ill adult patients admitted to the medical-surgical ICU with CVC inserted were included in this observational prospective study. After catheter removal we performed duplex ultrasound examination to assess the patency of the vein and establish if CR-DVT was present. Results. A total number of 308 catheters met the inclusion criteria of which 198 were included in the statistical analysis. The CVC was inserted into a subclavian vein (SCV) in 139 (70%) cases and in an internal jugular vein (IJV) in 59 (30%) cases. The 28-day mortality rate was 14.1%. We found CR-DVT during duplex ultrasound examination in 47 (26%) of all cases. 33 (70%) of the CR-DVT were diagnosed in the IJV and 14 (30%) in the SCV. The risk factors for the development of CR-DVT we identified included cannulation of the IJV and the use of treatment dose of LMWH. The effect of CR-DVT on 28-day mortality was not statistically significant. Conclusion. The risk factors for CR-DVT we identified were IJV as a site for CVC cannulation and the use of therapeutic anticoagulation prior to cannulation. Our recommendation would be preferential cannulation of a subclavian vein as opposed to an internal jugular vein in order to reduce the risk of CR-DVT.

Links

LM2015090, research and development project

Name: Český národní uzel Evropské sítě infrastruktur klinického výzkumu (Acronym: CZECRIN)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

HRDÝ, Ondřej, Eva STRAŽEVSKÁ, Petr SUK, Robert VACH, Radim KARLÍK, Jiří JARKOVSKÝ, Igor SAS and Roman GÁL. Central venous catheter-related thrombosis in intensive care patients - incidence and risk factors: A prospective observational study. Biomedical Papers, Olomouc: Palacky University. Olomouc: Palacky University, 2017, vol. 161, No 4, p. 369-373. ISSN 1213-8118. Available from: https://dx.doi.org/10.5507/bp.2017.034.

@article{1401272,
   author = {Hrdý, Ondřej and Straževská, Eva and Suk, Petr and Vach, Robert and Karlík, Radim and Jarkovský, Jiří and Sas, Igor and Gál, Roman},
   article_location = {Olomouc},
   article_number = {4},
   doi = {http://dx.doi.org/10.5507/bp.2017.034},
   keywords = {central venous catheter; deep vein thrombosis; risk factors; critical care},
   language = {eng},
   issn = {1213-8118},
   journal = {Biomedical Papers, Olomouc: Palacky University},
   title = {Central venous catheter-related thrombosis in intensive care patients - incidence and risk factors: A prospective observational study},
   url = {http://dx.doi.org/10.5507/bp.2017.034},
   volume = {161},
   year = {2017}
}

TY  - JOUR
ID  - 1401272
AU  - Hrdý, Ondřej - Straževská, Eva - Suk, Petr - Vach, Robert - Karlík, Radim - Jarkovský, Jiří - Sas, Igor - Gál, Roman
PY  - 2017
TI  - Central venous catheter-related thrombosis in intensive care patients - incidence and risk factors: A prospective observational study
JF  - Biomedical Papers, Olomouc: Palacky University
VL  - 161
IS  - 4
SP  - 369-373
EP  - 369-373
PB  - Palacky University
SN  - 12138118
KW  - central venous catheter
KW  - deep vein thrombosis
KW  - risk factors
KW  - critical care
UR  - http://dx.doi.org/10.5507/bp.2017.034
L2  - http://dx.doi.org/10.5507/bp.2017.034
N2  - Background. One of the complications associated with central venous catheter (CVC) placement is catheter related deep vein thrombosis (CR-DVT). However a literature search revealed little evidence of this recognised complication. The primary aim of this study was to establish the incidence rate and risk factors for the development of CR-DVT in our critically ill adult patients. Methods. All critically ill adult patients admitted to the medical-surgical ICU with CVC inserted were included in this observational prospective study. After catheter removal we performed duplex ultrasound examination to assess the patency of the vein and establish if CR-DVT was present. Results. A total number of 308 catheters met the inclusion criteria of which 198 were included in the statistical analysis. The CVC was inserted into a subclavian vein (SCV) in 139 (70%) cases and in an internal jugular vein (IJV) in 59 (30%) cases. The 28-day mortality rate was 14.1%. We found CR-DVT during duplex ultrasound examination in 47 (26%) of all cases. 33 (70%) of the CR-DVT were diagnosed in the IJV and 14 (30%) in the SCV. The risk factors for the development of CR-DVT we identified included cannulation of the IJV and the use of treatment dose of LMWH. The effect of CR-DVT on 28-day mortality was not statistically significant. Conclusion. The risk factors for CR-DVT we identified were IJV as a site for CVC cannulation and the use of therapeutic anticoagulation prior to cannulation. Our recommendation would be preferential cannulation of a subclavian vein as opposed to an internal jugular vein in order to reduce the risk of CR-DVT.
ER  -

HRDÝ, Ondřej, Eva STRAŽEVSKÁ, Petr SUK, Robert VACH, Radim KARLÍK, Jiří JARKOVSKÝ, Igor SAS and Roman GÁL. Central venous catheter-related thrombosis in intensive care patients - incidence and risk factors: A prospective observational study. \textit{Biomedical Papers, Olomouc: Palacky University}. Olomouc: Palacky University, 2017, vol.~161, No~4, p.~369-373. ISSN~1213-8118. Available from: https://dx.doi.org/10.5507/bp.2017.034.

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