Detailed Information on Publication Record
2017
Serological diagnostics in the detection of IgG autoantibodies against human collagen VII in epidermolysis bullosa acquisita: a multicentre analysis
SCHMIDT, T., M. HOCH, S.S. LOFTI JAD, F. SOLIMANI, G. DI ZENZO et. al.Basic information
Original name
Serological diagnostics in the detection of IgG autoantibodies against human collagen VII in epidermolysis bullosa acquisita: a multicentre analysis
Authors
SCHMIDT, T. (276 Germany), M. HOCH (276 Germany), S.S. LOFTI JAD (276 Germany), F. SOLIMANI (276 Germany), G. DI ZENZO (380 Italy), A.V. MARZANO (380 Italy), M. GOEBELER (276 Germany), E. COZZANI (380 Italy), J.S. KERN (276 Germany), C. SITARU (276 Germany), I. LAKOŠ JUKIĆ (191 Croatia), M. SÁRDY (276 Germany), S. UZUN (792 Turkey), Hana JEDLIČKOVÁ (203 Czech Republic, guarantor, belonging to the institution), R. GLÄSER (276 Germany), M. KANEDA (392 Japan), R. EMING (276 Germany), G. GÖPEL (276 Germany), N. ISHII (392 Japan), B. GREENE (276 Germany), T. HASHIMOTO (392 Japan) and M. HERTL (276 Germany)
Edition
British Journal of Dermatology, Hoboken, Wiley, 2017, 0007-0963
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30216 Dermatology and venereal diseases
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 6.129
RIV identification code
RIV/00216224:14110/17:00099150
Organization unit
Faculty of Medicine
UT WoS
000419479300057
Keywords in English
Epidermolysis bullosa acquisita
Tags
Tags
International impact, Reviewed
Změněno: 20/3/2018 17:59, Soňa Böhmová
Abstract
V originále
Epidermolysis bullosa acquisita (EBA) is a rare, potentially devastating autoimmune disease of the skin. IgG autoantibodies directed against type VII collagen (Col7), the major component of anchoring fibrils, induce skin fragility leading to cutaneous and mucocutaneous blister formation, which is mostly of a scarring phenotype. Thus, powerful and reproducible diagnostic assays are critical to establish the diagnosis of EBA early to avoid irreversible sequelae.