SCHMIDT, T., M. HOCH, S.S. LOFTI JAD, F. SOLIMANI, G. DI ZENZO, A.V. MARZANO, M. GOEBELER, E. COZZANI, J.S. KERN, C. SITARU, I. LAKOŠ JUKIĆ, M. SÁRDY, S. UZUN, Hana JEDLIČKOVÁ, R. GLÄSER, M. KANEDA, R. EMING, G. GÖPEL, N. ISHII, B. GREENE, T. HASHIMOTO and M. HERTL. Serological diagnostics in the detection of IgG autoantibodies against human collagen VII in epidermolysis bullosa acquisita: a multicentre analysis. British Journal of Dermatology. Hoboken: Wiley, 2017, vol. 177, No 6, p. 1683-1692. ISSN 0007-0963. Available from: https://dx.doi.org/10.1111/bjd.15800.
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Basic information
Original name Serological diagnostics in the detection of IgG autoantibodies against human collagen VII in epidermolysis bullosa acquisita: a multicentre analysis
Authors SCHMIDT, T. (276 Germany), M. HOCH (276 Germany), S.S. LOFTI JAD (276 Germany), F. SOLIMANI (276 Germany), G. DI ZENZO (380 Italy), A.V. MARZANO (380 Italy), M. GOEBELER (276 Germany), E. COZZANI (380 Italy), J.S. KERN (276 Germany), C. SITARU (276 Germany), I. LAKOŠ JUKIĆ (191 Croatia), M. SÁRDY (276 Germany), S. UZUN (792 Turkey), Hana JEDLIČKOVÁ (203 Czech Republic, guarantor, belonging to the institution), R. GLÄSER (276 Germany), M. KANEDA (392 Japan), R. EMING (276 Germany), G. GÖPEL (276 Germany), N. ISHII (392 Japan), B. GREENE (276 Germany), T. HASHIMOTO (392 Japan) and M. HERTL (276 Germany).
Edition British Journal of Dermatology, Hoboken, Wiley, 2017, 0007-0963.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30216 Dermatology and venereal diseases
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 6.129
RIV identification code RIV/00216224:14110/17:00099150
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1111/bjd.15800
UT WoS 000419479300057
Keywords in English Epidermolysis bullosa acquisita
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 20/3/2018 17:59.
Abstract
Epidermolysis bullosa acquisita (EBA) is a rare, potentially devastating autoimmune disease of the skin. IgG autoantibodies directed against type VII collagen (Col7), the major component of anchoring fibrils, induce skin fragility leading to cutaneous and mucocutaneous blister formation, which is mostly of a scarring phenotype. Thus, powerful and reproducible diagnostic assays are critical to establish the diagnosis of EBA early to avoid irreversible sequelae.
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