a 2017

Non-invasive estimation of arterial stiffness in healthy and asthmatic children - comparison of the methods: a pilot study.

BUDINSKAYA, Ksenia, Jana SVAČINOVÁ, Jana HRUŠKOVÁ, Zuzana KUBECOVÁ, Vojtěch SVÍZELA et. al.

Basic information

Original name

Non-invasive estimation of arterial stiffness in healthy and asthmatic children - comparison of the methods: a pilot study.

Name in Czech

Neinvazivní stanovení parametrů cévní stěny u děti s astma bronchiale: pilotní studie.

Authors

Edition

Federation of Europian Physiological Societies 2017, 2017

Other information

Type of outcome

Konferenční abstrakt

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 5.930

ISSN

UT WoS

000408842000143

Keywords in English

arterial stiffness, pulse wave velocity, augmentation index, cardio-ankle index
Změněno: 30/1/2018 13:20, Xenie Budínská, Ph.D.

Abstract

V originále

Questions Asthma is an inflammatory disease that affects not only lungs but other organ system, e.g. a cardiovascular system. Arterial stiffness is a subclinical predictor of cardiovascular diseases. Its measurement is carried out by applanation tonometry (European countries) with such main parameters as pulse wave velocity (PWV) and augmentation index (AI) as well as measurement of Cardio-ankle index (CAVI) outside Europe. The aim of our study is to estimate arterial stiffness in asthmatic and healthy children using two methods of its measurement and compare them. Methods We measured asthmatic children (group A, 52 respondents) and control group (C, 71 respondents) of the same age, systolic (SBP), diastolic (DBP) blood pressure and body mass index (BMI). For each respondent we measured SPB, DPB, PWV, AI and AI standardized on pulse height and heart rate (AIx75) on the dominant side with Sphygmocor device (AtCor Medical, Australia). All measurements were calibrated by oscillometric blood pressure measurement on the brachial artery (Omron, HEM-907-E, Japan) on the same side. The CAVI was measured with VaSera device (Fukuda Denshi, Japan). The Statistic 13 software was used for statistical analysis. Result There were significant differences in AIx75 (3.0±10.9 vs. -2.0±10.6; p<0.05), PWV (6.6±1.1 vs. 7.2±1.4; p<0.05), CAVI (4.5±0.9 vs. 4.9±0.6; p<0.05) between A and C, and significant correlation between PWV and CAVI (p<0.05). Conclusion We can conclude that asthma bronchiale and its treatment changed the properties of vessels in children comparing to the healthy group. Our study shows that both methods reflect the changes in arterial stiffness.

Links

MUNI/A/1355/2016, interní kód MU
Name: Kardiovaskulární systém očima molekulární fyziologie
Investor: Masaryk University, Category A