SCHWARTE, Andreas, Maika GENZ, Lilly SKALDEN, Alberto NOBILI, Clare VICKERS, Okke MELSE, Remko KUIPERS, Henk_jan JOOSTEN, Jan ŠTOURAČ, Jaroslav BENDL, Jon BLACK, Peter HAASE, Coos BAAKMAN, Jiří DAMBORSKÝ, Uwe BORNSCHEUER, Gert VRIEND and Hanka VENSELAAR. NewProt – a Protein Engineering Portal. PROTEIN ENGINEERING, DESIGN & SELECTION. Oxford: OXFORD UNIV PRESS, 2017, vol. 30, No 6, p. 441-447. ISSN 1741-0126. Available from: https://dx.doi.org/10.1093/protein/gzx024.
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Basic information
Original name NewProt – a Protein Engineering Portal
Authors SCHWARTE, Andreas (276 Germany), Maika GENZ (276 Germany), Lilly SKALDEN (276 Germany), Alberto NOBILI (276 Germany), Clare VICKERS (276 Germany), Okke MELSE (276 Germany), Remko KUIPERS (528 Netherlands), Henk_jan JOOSTEN (528 Netherlands), Jan ŠTOURAČ (203 Czech Republic, belonging to the institution), Jaroslav BENDL (203 Czech Republic, belonging to the institution), Jon BLACK (528 Netherlands), Peter HAASE (276 Germany), Coos BAAKMAN (528 Netherlands), Jiří DAMBORSKÝ (203 Czech Republic, guarantor, belonging to the institution), Uwe BORNSCHEUER (276 Germany), Gert VRIEND (528 Netherlands) and Hanka VENSELAAR (528 Netherlands).
Edition PROTEIN ENGINEERING, DESIGN & SELECTION, Oxford, OXFORD UNIV PRESS, 2017, 1741-0126.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10606 Microbiology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.881
RIV identification code RIV/00216224:14310/17:00099438
Organization unit Faculty of Science
Doi http://dx.doi.org/10.1093/protein/gzx024
UT WoS 000404476100004
Keywords in English mutant analysis; portal; protein design; protein engineering; web server
Tags NZ, rivok
Changed by Changed by: Ing. Nicole Zrilić, učo 240776. Changed: 9/4/2018 16:36.
Abstract
The NewProt protein engineering portal is a one-stop-shop for in silico protein engineering. It gives access to a large number of servers that compute a wide variety of protein structure characteristics supporting work on the modification of proteins through the introduction of (multiple) point mutations. The results can be inspected through multiple visualizers. The HOPE software is included to indicate mutations with possible undesired side effects. The Hotspot Wizard software is embedded for the design of mutations that modify a proteins’ activity, specificity, or stability. The NewProt portal is freely accessible at http://newprot.cmbi.umcn.nl/ and http://newprot.fluidops.net/.
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