J 2017

NewProt – a Protein Engineering Portal

SCHWARTE, Andreas, Maika GENZ, Lilly SKALDEN, Alberto NOBILI, Clare VICKERS et. al.

Basic information

Original name

NewProt – a Protein Engineering Portal

Authors

SCHWARTE, Andreas (276 Germany), Maika GENZ (276 Germany), Lilly SKALDEN (276 Germany), Alberto NOBILI (276 Germany), Clare VICKERS (276 Germany), Okke MELSE (276 Germany), Remko KUIPERS (528 Netherlands), Henk_jan JOOSTEN (528 Netherlands), Jan ŠTOURAČ (203 Czech Republic, belonging to the institution), Jaroslav BENDL (203 Czech Republic, belonging to the institution), Jon BLACK (528 Netherlands), Peter HAASE (276 Germany), Coos BAAKMAN (528 Netherlands), Jiří DAMBORSKÝ (203 Czech Republic, guarantor, belonging to the institution), Uwe BORNSCHEUER (276 Germany), Gert VRIEND (528 Netherlands) and Hanka VENSELAAR (528 Netherlands)

Edition

PROTEIN ENGINEERING, DESIGN & SELECTION, Oxford, OXFORD UNIV PRESS, 2017, 1741-0126

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10606 Microbiology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 1.881

RIV identification code

RIV/00216224:14310/17:00099438

Organization unit

Faculty of Science

UT WoS

000404476100004

Keywords in English

mutant analysis; portal; protein design; protein engineering; web server

Tags

Změněno: 9/4/2018 16:36, Ing. Nicole Zrilić

Abstract

V originále

The NewProt protein engineering portal is a one-stop-shop for in silico protein engineering. It gives access to a large number of servers that compute a wide variety of protein structure characteristics supporting work on the modification of proteins through the introduction of (multiple) point mutations. The results can be inspected through multiple visualizers. The HOPE software is included to indicate mutations with possible undesired side effects. The Hotspot Wizard software is embedded for the design of mutations that modify a proteins’ activity, specificity, or stability. The NewProt portal is freely accessible at http://newprot.cmbi.umcn.nl/ and http://newprot.fluidops.net/.