k 2017

Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis

JANČAŘÍKOVÁ, Gita, Josef HOUSER, Pavel DOBEŠ, Pavel HYRŠL, Michaela WIMMEROVÁ et. al.

Basic information

Original name

Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis

Name in Czech

Studium nově identifikovaného lektinu PHL z Photorhabdus asymbiotica a jeho možná role v patogenitě

Name (in English)

Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis

Authors

JANČAŘÍKOVÁ, Gita (203 Czech Republic, belonging to the institution), Josef HOUSER (203 Czech Republic, belonging to the institution), Pavel DOBEŠ (203 Czech Republic, belonging to the institution), Pavel HYRŠL (203 Czech Republic, belonging to the institution) and Michaela WIMMEROVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

XVIII. setkání biochemiků a molekulárních biologů, 2017

Other information

Language

Czech

Type of outcome

Prezentace na konferencích

Field of Study

10600 1.6 Biological sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14310/17:00095418

Organization unit

Faculty of Science

ISBN

978-80-210-8765-1

Keywords (in Czech)

Lektin; hmyz; lrevní skupiny; sacharidy; Phothorabdus asymbiotica; strukturně-funkční studie; imunitní odpověď

Keywords in English

lectins; insects; blood groups; carbohydrates; Phothorabdus asymbiotica; functional-structure study; immune response; nematode infections
Změněno: 24/1/2018 10:05, Mgr. Gita Paulíková, Ph.D.

Abstract

ORIG EN

V originále

Our project is focused on study of a newly identified bangle lectin from the Photorabdus asymbiotica bacterium (PHL). Photorabdus asymbiotica belongs with other three species to the Photorabdus genus. These 3 species are characterized as strictly virulent insect pathogens. In contrast, P. asymbiotica is also a human pathogen, which causes locally invasive soft tissue and disseminated bacterimic infections. We have identified a new putative lectin in the P. asymbiotica genome, determined binding properties and structure and also its influence on host immunity.

In English

Our project is focused on study of a newly identified bangle lectin from the Photorabdus asymbiotica bacterium (PHL). Photorabdus asymbiotica belongs with other three species to the Photorabdus genus. These 3 species are characterized as strictly virulent insect pathogens. In contrast, P. asymbiotica is also a human pathogen, which causes locally invasive soft tissue and disseminated bacterimic infections. We have identified a new putative lectin in the P. asymbiotica genome, determined binding properties and structure and also its influence on host immunity.

Links

GA13-25401S, research and development project
Name: Studium proteinů z patogenů zapojených do rozpoznávání hostitelského organismu
Investor: Czech Science Foundation
LM2015043, research and development project
Name: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB)
Investor: Ministry of Education, Youth and Sports of the CR
LQ1601, research and development project
Name: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR