JANČAŘÍKOVÁ, Gita, Josef HOUSER, Pavel DOBEŠ, Pavel HYRŠL and Michaela WIMMEROVÁ. Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis. In XVIII. setkání biochemiků a molekulárních biologů. 2017. ISBN 978-80-210-8765-1.
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Basic information
Original name Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis
Name in Czech Studium nově identifikovaného lektinu PHL z Photorhabdus asymbiotica a jeho možná role v patogenitě
Name (in English) Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis
Authors JANČAŘÍKOVÁ, Gita (203 Czech Republic, belonging to the institution), Josef HOUSER (203 Czech Republic, belonging to the institution), Pavel DOBEŠ (203 Czech Republic, belonging to the institution), Pavel HYRŠL (203 Czech Republic, belonging to the institution) and Michaela WIMMEROVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition XVIII. setkání biochemiků a molekulárních biologů, 2017.
Other information
Original language Czech
Type of outcome Presentations at conferences
Field of Study 10600 1.6 Biological sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14310/17:00095418
Organization unit Faculty of Science
ISBN 978-80-210-8765-1
Keywords (in Czech) Lektin; hmyz; lrevní skupiny; sacharidy; Phothorabdus asymbiotica; strukturně-funkční studie; imunitní odpověď
Keywords in English lectins; insects; blood groups; carbohydrates; Phothorabdus asymbiotica; functional-structure study; immune response; nematode infections
Changed by Changed by: Mgr. Gita Paulíková, Ph.D., učo 175742. Changed: 24/1/2018 10:05.
Abstract
Our project is focused on study of a newly identified bangle lectin from the Photorabdus asymbiotica bacterium (PHL). Photorabdus asymbiotica belongs with other three species to the Photorabdus genus. These 3 species are characterized as strictly virulent insect pathogens. In contrast, P. asymbiotica is also a human pathogen, which causes locally invasive soft tissue and disseminated bacterimic infections. We have identified a new putative lectin in the P. asymbiotica genome, determined binding properties and structure and also its influence on host immunity.
Abstract (in English)
Our project is focused on study of a newly identified bangle lectin from the Photorabdus asymbiotica bacterium (PHL). Photorabdus asymbiotica belongs with other three species to the Photorabdus genus. These 3 species are characterized as strictly virulent insect pathogens. In contrast, P. asymbiotica is also a human pathogen, which causes locally invasive soft tissue and disseminated bacterimic infections. We have identified a new putative lectin in the P. asymbiotica genome, determined binding properties and structure and also its influence on host immunity.
Links
GA13-25401S, research and development projectName: Studium proteinů z patogenů zapojených do rozpoznávání hostitelského organismu
Investor: Czech Science Foundation
LM2015043, research and development projectName: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB)
Investor: Ministry of Education, Youth and Sports of the CR
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
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