Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis
JANČAŘÍKOVÁ, Gita, Josef HOUSER, Pavel DOBEŠ, Pavel HYRŠL and Michaela WIMMEROVÁ. Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis. In XVIII. setkání biochemiků a molekulárních biologů. 2017. ISBN 978-80-210-8765-1. |
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Basic information | |
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Original name | Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis |
Name in Czech | Studium nově identifikovaného lektinu PHL z Photorhabdus asymbiotica a jeho možná role v patogenitě |
Name (in English) | Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis |
Authors | JANČAŘÍKOVÁ, Gita (203 Czech Republic, belonging to the institution), Josef HOUSER (203 Czech Republic, belonging to the institution), Pavel DOBEŠ (203 Czech Republic, belonging to the institution), Pavel HYRŠL (203 Czech Republic, belonging to the institution) and Michaela WIMMEROVÁ (203 Czech Republic, guarantor, belonging to the institution). |
Edition | XVIII. setkání biochemiků a molekulárních biologů, 2017. |
Other information | |
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Original language | Czech |
Type of outcome | Presentations at conferences |
Field of Study | 10600 1.6 Biological sciences |
Country of publisher | Czech Republic |
Confidentiality degree | is not subject to a state or trade secret |
RIV identification code | RIV/00216224:14310/17:00095418 |
Organization unit | Faculty of Science |
ISBN | 978-80-210-8765-1 |
Keywords (in Czech) | Lektin; hmyz; lrevní skupiny; sacharidy; Phothorabdus asymbiotica; strukturně-funkční studie; imunitní odpověď |
Keywords in English | lectins; insects; blood groups; carbohydrates; Phothorabdus asymbiotica; functional-structure study; immune response; nematode infections |
Changed by | Changed by: Mgr. Gita Paulíková, Ph.D., učo 175742. Changed: 24/1/2018 10:05. |
Abstract |
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Our project is focused on study of a newly identified bangle lectin from the Photorabdus asymbiotica bacterium (PHL). Photorabdus asymbiotica belongs with other three species to the Photorabdus genus. These 3 species are characterized as strictly virulent insect pathogens. In contrast, P. asymbiotica is also a human pathogen, which causes locally invasive soft tissue and disseminated bacterimic infections. We have identified a new putative lectin in the P. asymbiotica genome, determined binding properties and structure and also its influence on host immunity. |
Abstract (in English) |
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Our project is focused on study of a newly identified bangle lectin from the Photorabdus asymbiotica bacterium (PHL). Photorabdus asymbiotica belongs with other three species to the Photorabdus genus. These 3 species are characterized as strictly virulent insect pathogens. In contrast, P. asymbiotica is also a human pathogen, which causes locally invasive soft tissue and disseminated bacterimic infections. We have identified a new putative lectin in the P. asymbiotica genome, determined binding properties and structure and also its influence on host immunity. |
Links | |
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GA13-25401S, research and development project | Name: Studium proteinů z patogenů zapojených do rozpoznávání hostitelského organismu |
Investor: Czech Science Foundation | |
LM2015043, research and development project | Name: Česká infrastruktura pro integrativní strukturní biologii (Acronym: CIISB) |
Investor: Ministry of Education, Youth and Sports of the CR | |
LQ1601, research and development project | Name: CEITEC 2020 (Acronym: CEITEC2020) |
Investor: Ministry of Education, Youth and Sports of the CR |
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