Future health systems, besides traditional areas defined and addressed since 1980, face the advent of Proactive, Predictive, Prospective, Preventive, Participative and Personalized health care (HC). Reliable e-health platforms can help us with these challenges. They should be designed and implemented in a way to help ordinary people achieve extraordinary results. Even the best projects addressing HC systems improvement are not automatically qualified for implementation unless adopted by policy makers. The introduction of strategies with a potential for healthcare systems improvement to policy makers is necessary but difficult because of the complexity of the addressed issue. Illustrated on four projects, selected from the 25 the author participated in, from 1993 to 2016, principles, processes and attitudes found beneficial for successful policy implementation in various healthcare environments, are presented, to help with the integration of reliable electronic healthcare platforms into coming healthcare systems.