STROUHAL, Michal, Jan OPPELT, Lenka MIKALOVÁ, Natasha ARORA, Kay NIESELT, Fernando GONZÁLEZ-CANDELAS and David ŠMAJS. Reanalysis of Chinese Treponema pallidum samples: all Chinese samples cluster with SS14-like group of syphilis-causing treponemes. BMC Research Notes. London: BioMed Central Ltd., 2018, vol. 11, No 1, p. 1-5. ISSN 1756-0500. Available from: https://dx.doi.org/10.1186/s13104-017-3106-7.
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Basic information
Original name Reanalysis of Chinese Treponema pallidum samples: all Chinese samples cluster with SS14-like group of syphilis-causing treponemes
Authors STROUHAL, Michal (203 Czech Republic, belonging to the institution), Jan OPPELT (203 Czech Republic, belonging to the institution), Lenka MIKALOVÁ (203 Czech Republic, belonging to the institution), Natasha ARORA (756 Switzerland), Kay NIESELT (276 Germany), Fernando GONZÁLEZ-CANDELAS (724 Spain) and David ŠMAJS (203 Czech Republic).
Edition BMC Research Notes, London, BioMed Central Ltd. 2018, 1756-0500.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10606 Microbiology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14110/18:00100799
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1186/s13104-017-3106-7
Keywords in English Genome sequencing; Phylogenetic analysis; Single nucleotide variant; SyphilisTreponema pallidum
Tags EL OK, rivok
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 25/5/2018 16:28.
Abstract
Treponema pallidum subsp. pallidum (TPA) is the causative agent of syphilis. Genetic analyses of TPA reference strains and human clinical isolates have revealed two genetically distinct groups of syphilis-causing treponemes, called Nichols-like and SS14-like groups. So far, no genetic intermediates, i.e. strains containing a mixed pattern of Nichols-like and SS14-like genomic sequences, have been identified. Recently, Sun et al. (Oncotarget 2016. https://doi.org/10.18632/oncotarget.10154) described a new “phylogenetic group” (called Lineage 2) among Chinese TPA strains. This lineage exhibited a “mosaic genomic structure” of Nichols-like and SS14-like lineages.
Links
GA17-25455S, research and development projectName: Studium genomů patogenních treponem na základě analýzy jednotlivých buněk
Investor: Czech Science Foundation
MUNI/A/1171/2015, interní kód MUName: Molekulárně buněčná biologie pro biomedicínu
Investor: Masaryk University, Category A
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