PARUCH, Kamil, Benoit, Jean-Pierre CARBAIN, Štěpán HAVEL, Jiří DAMBORSKÝ, Jan BREZOVSKÝ, Lukáš DANIEL, Alexandra SISÁKOVÁ, Fedor NIKULENKOV and Lumír KREJČÍ. Pyrazolotriazines as inhibitors of nucleases. 2017.
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Basic information
Original name Pyrazolotriazines as inhibitors of nucleases
Authors PARUCH, Kamil (203 Czech Republic, belonging to the institution), Benoit, Jean-Pierre CARBAIN (250 France, belonging to the institution), Štěpán HAVEL (203 Czech Republic, belonging to the institution), Jiří DAMBORSKÝ (203 Czech Republic, belonging to the institution), Jan BREZOVSKÝ (203 Czech Republic, belonging to the institution), Lukáš DANIEL (203 Czech Republic, belonging to the institution), Alexandra SISÁKOVÁ (703 Slovakia, belonging to the institution), Fedor NIKULENKOV (203 Czech Republic, belonging to the institution) and Lumír KREJČÍ (203 Czech Republic, guarantor, belonging to the institution).
Edition Number: EP2957562, Publisher: European Patent Office, Place of publication: Munich, Owner's name: Masarykova univerzita, 2017.
Other information
Original language English
Type of outcome Patent
Field of Study 10600 1.6 Biological sciences
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14310/17:00099613
Organization unit Faculty of Science
Keywords in English Pyrazolotriazines
Tags EL OK, NZ, rivok
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 17/4/2018 14:32.
Abstract
The present invention relates to substituted heterocycles as inhibitors of nudeases MUS81 and MRE11, pharmaceutical compositions containing the compounds, and pharmaceutical use of the compounds and compositions in the treatment of the diseases such as, for example, cancer.
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