LIND, M., A. HAYES, M. CAPRNDA, D. PETROVIC, L. RODRIGO, Peter KRUŽLIAK and A. ZULLI. Inducible nitric oxide synthase: Good or bad? BIOMEDICINE & PHARMACOTHERAPY. PARIS: ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017, vol. 93, SEP 2017, p. 370-375. ISSN 0753-3322. Available from: https://dx.doi.org/10.1016/j.biopha.2017.06.036. |
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@article{1406937, author = {Lind, M. and Hayes, A. and Caprnda, M. and Petrovic, D. and Rodrigo, L. and Kružliak, Peter and Zulli, A.}, article_location = {PARIS}, article_number = {SEP 2017}, doi = {http://dx.doi.org/10.1016/j.biopha.2017.06.036}, keywords = {Nitric oxide synthase (NOS); Inducible NOS (iNOS); Endothelial NOS (eNOS); Cyclooxygenase-2 (COX-2); COX-2; Oxidative stress; Cardiovascular diseases}, language = {eng}, issn = {0753-3322}, journal = {BIOMEDICINE & PHARMACOTHERAPY}, title = {Inducible nitric oxide synthase: Good or bad?}, volume = {93}, year = {2017} }
TY - JOUR ID - 1406937 AU - Lind, M. - Hayes, A. - Caprnda, M. - Petrovic, D. - Rodrigo, L. - Kružliak, Peter - Zulli, A. PY - 2017 TI - Inducible nitric oxide synthase: Good or bad? JF - BIOMEDICINE & PHARMACOTHERAPY VL - 93 IS - SEP 2017 SP - 370-375 EP - 370-375 PB - ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER SN - 07533322 KW - Nitric oxide synthase (NOS) KW - Inducible NOS (iNOS) KW - Endothelial NOS (eNOS) KW - Cyclooxygenase-2 (COX-2) KW - COX-2 KW - Oxidative stress KW - Cardiovascular diseases N2 - Nitric oxide synthases (NOS) are a family of isoforms responsible for the synthesis of the potent dilator nitric oxide (NO). Expression of inducible NOS (iNOS) occurs in conditions of inflammation, and produces large amounts of NO. In pathological conditions iNOS is regarded as a harmful enzyme and is proposed to be a major contributor to diseases of the cardiovascular system such as atherosclerosis. In this review, we address the notion that iNOS is a detrimental enzyme in disease and discuss its potentially beneficial roles. Additionally, we describe other molecules associated with iNOS in diseases such as atherosclerosis, and current research on therapeutic inhibitors tested to reduced pathology associated with cardiovascular diseases (CVD). (C) 2017 Elsevier Masson SAS. All rights reserved. ER -
LIND, M., A. HAYES, M. CAPRNDA, D. PETROVIC, L. RODRIGO, Peter KRUŽLIAK and A. ZULLI. Inducible nitric oxide synthase: Good or bad? \textit{BIOMEDICINE \&{}amp; PHARMACOTHERAPY}. PARIS: ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2017, vol.~93, SEP 2017, p.~370-375. ISSN~0753-3322. Available from: https://dx.doi.org/10.1016/j.biopha.2017.06.036.
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