MARUSIC, A.P., I. LOCATELLI, A. MRHAR, M. CAPRNDA, L. GASPAR, M. ADAMEK, Peter KRUŽLIAK and D. PETROVIC. Influence of Prescribed Blood Products on the Incidence of Deep Vein Thrombosis and Pulmonary Embolism in Surgical Patients. Clinical and Applied Thrombosis-Hemostasis. Thousand Oaks: Sage Publications Inc., 2017, vol. 23, No 8, p. 938-942. ISSN 1076-0296. Available from: https://dx.doi.org/10.1177/1076029616689301.
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Basic information
Original name Influence of Prescribed Blood Products on the Incidence of Deep Vein Thrombosis and Pulmonary Embolism in Surgical Patients
Authors MARUSIC, A.P. (705 Slovenia), I. LOCATELLI (705 Slovenia), A. MRHAR (705 Slovenia), M. CAPRNDA (703 Slovakia), L. GASPAR (705 Slovenia), M. ADAMEK (616 Poland), Peter KRUŽLIAK (703 Slovakia, guarantor, belonging to the institution) and D. PETROVIC (705 Slovenia).
Edition Clinical and Applied Thrombosis-Hemostasis, Thousand Oaks, Sage Publications Inc. 2017, 1076-0296.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30205 Hematology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.852
RIV identification code RIV/00216224:14110/17:00099909
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1177/1076029616689301
UT WoS 000412901900006
Keywords in English prevention of venous thromboembolism; red blood cells; vitamin K; blood replacement
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 20/3/2018 15:27.
Abstract
Deep vein thrombosis (DVT) and pulmonary embolisms (PEs) are common complications after surgical procedures. The influence of prescribed blood products on the occurrence of DVT and PE was evaluated in postsurgical patients in this retrospective case-control study. The records of 286 surgical patients were analyzed: DVT (n = 52), PE (n = 92), and a control group (n = 142). The amounts of prescribed blood, blood products, and vitamin K were reviewed, together with appropriate prescribing of low-molecular-weight heparins. The influence of prescribed blood products on the occurrence of DVT or PE was analyzed using multinomial logistic regression. We demonstrated a significant difference between the test and control groups (P < .05) in relation to receiving packed red blood cells. Treatment with red blood cells was associated with an increased risk of PE but not DVT. Patients who developed PE after surgery were hospitalized for longer (median 10 days) than patients with DVT (median 6 days). There was no difference between the test and control groups concerning treatment with fresh frozen plasma. Inadequate thromboprophylaxis significantly increased the likelihood of DVT. There is a connection between receiving packed red blood cells and occurrence of postoperative PE in surgical patients. Thus, patients receiving red blood cells should be monitored more closely after surgery, as they are more likely to develop PE postoperatively.
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