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@article{1407078,
author = {Lobello, Cosimo and Janíková, Andrea and Křen, Leoš and Hermanová, Markéta and ŠprlákováandPuková, Andrea and Krejčí, Jan and Pospíšilová, Šárka and Pytlík, Robert and Hamouzová, Michaela and Belada, David and Prochazka, Vit and Duras, Juraj and Móciková, Heidi and Trněný, Marek and Janíková, Andrea},
article_location = {Manchester},
article_number = {10},
doi = {http://dx.doi.org/10.14312/2052-4994.2017-13},
keywords = {cardiac lymphoma; anaplastic large cell lymphoma; ALK},
language = {eng},
issn = {2052-4994},
journal = {Journal of Cancer Research & Therapy},
title = {An anaplastic cardiac large cell lymphoma: A case report and analysis of cardiac involvement in newly diagnosed nonHodgkin’s lymphoma from the Czech Lymphoma Study Group (CLSG) database},
url = {http://nobleresearch.org/Doi/10.14312/2052-4994.2017-13},
volume = {5},
year = {2017}
}
TY - JOUR
ID - 1407078
AU - Lobello, Cosimo - Janíková, Andrea - Křen, Leoš - Hermanová, Markéta - Šprláková-Puková, Andrea - Krejčí, Jan - Pospíšilová, Šárka - Pytlík, Robert - Hamouzová, Michaela - Belada, David - Prochazka, Vit - Duras, Juraj - Móciková, Heidi - Trněný, Marek - Janíková, Andrea
PY - 2017
TI - An anaplastic cardiac large cell lymphoma: A case report and analysis of cardiac involvement in newly diagnosed nonHodgkin’s lymphoma from the Czech Lymphoma Study Group (CLSG) database
JF - Journal of Cancer Research & Therapy
VL - 5
IS - 10
SP - 66-71
EP - 66-71
PB - NobleResearch Publishers Limited
SN - 20524994
KW - cardiac lymphoma
KW - anaplastic large cell lymphoma
KW - ALK
UR - http://nobleresearch.org/Doi/10.14312/2052-4994.2017-13
N2 - We report a rare case of anaplastic large cell ALK+ lymphoma (ALCL) with initial asymptomatic cardiac involvement. A 59-year-old male with infiltration of the right ventricular wall underwent standard combined chemotherapy (CHOP) and achieved remission without significant cardiac impairment. Additionally, we report the actual incidence of cardiac lymphoma in newly diagnosed non-Hodgkin Lymphomas (NHLs). In total, 16 patients with cardiac lymphoma were found (0.1% NHLs) in the Czech Lymphoma Study Group database. DLBCL was the most frequent histology subtype (50%), and ALCL was identified in 12.5% of cases. At initial diagnosis, the median age was 55.5 (range 21-74) years and 59% were men. None of the 16 patients with cardiac involvement had isolated heart lymphoma. The response to first-line therapy was 79% in 14/16 evaluable patients. The median progression-free survival and overall survival were nearly the same -approximately 3.5 years (range; 0.05-16.7ys), while the median follow up was 4 years.
ER -
LOBELLO, Cosimo, Andrea JANÍKOVÁ, Leoš KŘEN, Markéta HERMANOVÁ, Andrea ŠPRLÁKOVÁ-PUKOVÁ, Jan KREJČÍ, Šárka POSPÍŠILOVÁ, Robert PYTLÍK, Michaela HAMOUZOVÁ, David BELADA, Vit PROCHAZKA, Juraj DURAS, Heidi MÓCIKOVÁ a Marek TRNĚNÝ. An anaplastic cardiac large cell lymphoma: A case report and analysis of cardiac involvement in newly diagnosed nonHodgkin’s lymphoma from the Czech Lymphoma Study Group (CLSG) database. \textit{Journal of Cancer Research \&{} Therapy}. Manchester: NobleResearch Publishers Limited, roč.~5, č.~10, s.~66-71. ISSN~2052-4994. doi:10.14312/2052-4994.2017-13. 2017.
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