KUSHKEVYCH, Ivan, Monika VÍTĚZOVÁ, Jiri KOS, Peter KOLLÁR and Josef JAMPI­LEK. Effect of selected 8-hydroxyquinoline-2-carboxanilides on viability and sulfate metabolism of Desulfovibrio piger. Journal of Applied Biomedicine. Jihočeská univerzita v Českých Budějovicích, 2018, vol. 16, No 3, p. 241-246. ISSN 1214-021X. Available from: https://dx.doi.org/10.1016/j.jab.2018.01.004.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Effect of selected 8-hydroxyquinoline-2-carboxanilides on viability and sulfate metabolism of Desulfovibrio piger
Authors KUSHKEVYCH, Ivan (804 Ukraine, belonging to the institution), Monika VÍTĚZOVÁ (203 Czech Republic, belonging to the institution), Jiri KOS (203 Czech Republic), Peter KOLLÁR (203 Czech Republic) and Josef JAMPI­LEK (203 Czech Republic).
Edition Journal of Applied Biomedicine, Jihočeská univerzita v Českých Budějovicích, 2018, 1214-021X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10606 Microbiology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.573
RIV identification code RIV/00216224:14310/18:00102287
Organization unit Faculty of Science
Doi http://dx.doi.org/10.1016/j.jab.2018.01.004
UT WoS 000440056300012
Keywords in English Sulfate-reducing bacteria; Dissimilatory sulfate reduction; Inflammatory bowel disease; 8-hydroxyquinolines; Structure-activity relationships
Changed by Changed by: doc. Ivan Kushkevych, Ph.D., učo 238729. Changed: 5/4/2020 14:24.
Abstract
An increased number of sulfate-reducing bacteria is often isolated from faeces of patients with gastrointestinal diseases, which can be the cause of the development of bowel inflammation. Frequent use of antibiotics causes the resistance of intestinal microorganisms and ineffective treatment of these diseases. The antimicrobial activity and biological properties of the selected ring-substituted 8-hydroxyquinoline-2-carboxanilides against Desulfovibrio piger Vib-7 were studied. The addition of these compounds in the cultivation medium inhibited the bacterial growth and the process of sulfate reduction dose-dependently. A significant cytotoxic activity under the influence of ring-substituted 8-hydroxyquinoline-2-carboxanilides was determined.
Links
MUNI/A/0906/2016, interní kód MUName: Podpora výzkumné činnosti studentů Mikrobiologie a molekulární biotechnologie 1 (Acronym: SVMIK)
Investor: Masaryk University, Category A
PrintDisplayed: 6/10/2024 12:23