Detailed Information on Publication Record
2018
Effect of selected 8-hydroxyquinoline-2-carboxanilides on viability and sulfate metabolism of Desulfovibrio piger
KUSHKEVYCH, Ivan, Monika VÍTĚZOVÁ, Jiri KOS, Peter KOLLÁR, Josef JAMPILEK et. al.Basic information
Original name
Effect of selected 8-hydroxyquinoline-2-carboxanilides on viability and sulfate metabolism of Desulfovibrio piger
Authors
KUSHKEVYCH, Ivan (804 Ukraine, belonging to the institution), Monika VÍTĚZOVÁ (203 Czech Republic, belonging to the institution), Jiri KOS (203 Czech Republic), Peter KOLLÁR (203 Czech Republic) and Josef JAMPILEK (203 Czech Republic)
Edition
Journal of Applied Biomedicine, Jihočeská univerzita v Českých Budějovicích, 2018, 1214-021X
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10606 Microbiology
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 1.573
RIV identification code
RIV/00216224:14310/18:00102287
Organization unit
Faculty of Science
UT WoS
000440056300012
Keywords in English
Sulfate-reducing bacteria; Dissimilatory sulfate reduction; Inflammatory bowel disease; 8-hydroxyquinolines; Structure-activity relationships
Změněno: 5/4/2020 14:24, doc. Ivan Kushkevych, Ph.D.
Abstract
V originále
An increased number of sulfate-reducing bacteria is often isolated from faeces of patients with gastrointestinal diseases, which can be the cause of the development of bowel inflammation. Frequent use of antibiotics causes the resistance of intestinal microorganisms and ineffective treatment of these diseases. The antimicrobial activity and biological properties of the selected ring-substituted 8-hydroxyquinoline-2-carboxanilides against Desulfovibrio piger Vib-7 were studied. The addition of these compounds in the cultivation medium inhibited the bacterial growth and the process of sulfate reduction dose-dependently. A significant cytotoxic activity under the influence of ring-substituted 8-hydroxyquinoline-2-carboxanilides was determined.
Links
MUNI/A/0906/2016, interní kód MU |
|