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@article{1407843, author = {Sun, Xiaolong and Odyniec, Maria L. and Sedgwick, Adam C. and Lacina, Karel and Xu, Suying and Qiang, Taotao and Bull, Steven D. and Marken, Frank and James, Tony D.}, article_number = {6}, doi = {http://dx.doi.org/10.1039/c6qo00448b}, keywords = {FLUORESCENT-PROBES; LIVING CELLS; BORONIC ACID; IN-VIVO; INFLAMMATION; REPORTER; MODEL}, language = {eng}, issn = {2052-4129}, journal = {Organic Chemistry Frontiers}, title = {Reaction-based indicator displacement assay (RIA) for the colorimetric and fluorometric detection of hydrogen peroxide}, url = {http://pubs.rsc.org/en/content/articlepdf/2017/qo/c6qo00448b}, volume = {4}, year = {2017} }
TY - JOUR ID - 1407843 AU - Sun, Xiaolong - Odyniec, Maria L. - Sedgwick, Adam C. - Lacina, Karel - Xu, Suying - Qiang, Taotao - Bull, Steven D. - Marken, Frank - James, Tony D. PY - 2017 TI - Reaction-based indicator displacement assay (RIA) for the colorimetric and fluorometric detection of hydrogen peroxide JF - Organic Chemistry Frontiers VL - 4 IS - 6 SP - 1058-1062 EP - 1058-1062 SN - 20524129 KW - FLUORESCENT-PROBES KW - LIVING CELLS KW - BORONIC ACID KW - IN-VIVO KW - INFLAMMATION KW - REPORTER KW - MODEL UR - http://pubs.rsc.org/en/content/articlepdf/2017/qo/c6qo00448b L2 - http://pubs.rsc.org/en/content/articlepdf/2017/qo/c6qo00448b N2 - Based on the complexation of phenylboronic acid (PBA) with Alizarin Red S (ARS), we developed a new chemosensor for the detection of hydrogen peroxide (H2O2) in aqueous media. This platform has demonstrated its ability to detect H2O2 via colorimetric, fluorometric, and electrochemical measurements. The experimental observations reveal that the system displays a red-shifted visible colour change, on–off fluorescence response indicating release of indicator (ARS) and turn-on electrochemical signal indicating generation of phenol, after reaction with H2O2. With this work we have demonstrated that our reaction-based indicator displacement assay (RIA) systems, can be employed as an assay for H2O2 and hydrogen peroxide-related species for environmental and physiological detection. ER -
SUN, Xiaolong, Maria L. ODYNIEC, Adam C. SEDGWICK, Karel LACINA, Suying XU, Taotao QIANG, Steven D. BULL, Frank MARKEN and Tony D. JAMES. Reaction-based indicator displacement assay (RIA) for the colorimetric and fluorometric detection of hydrogen peroxide. \textit{Organic Chemistry Frontiers}. 2017, vol.~4, No~6, p.~1058-1062. ISSN~2052-4129. Available from: https://dx.doi.org/10.1039/c6qo00448b.
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