Introduction: Long-term mechanical heart support is the last stage of chronic heart failure treatment. The aim of the research was to evaluate how to what extent long-term mechanical heart support influences patient life quality. Methodology: The data have been acquired through a quantitative research method using the World Health Organization WHOQOL-BREF standardised questionnaire. Results: The research involved 51 patients (46 men and 5 women). The average age was 54.29 years. Seventeen respondents live with the HeartMate II long-term mechanical heart support and 34 respondents with HeartMate III. The average period from implantation is 15.76 months. In the domain of physical health it was established that the scores for individual age groups are below the BREF norm (except for the age group over 70 years). In the domain of emotions it was established that the indicators were slightly below the BREF norm in 3 of the 5 age groups and slightly above the BREF norm in 2 of the 5 age groups. In the domain of social relationships it was found that the age group of 18-29 years did not reach the BREF norm. In the domain of the surrounding environment all age groups exceeded the BREF norm value. Conclusion: Patients evaluate the quality of life after the implantation of long-term mechanical heart support in a positive way. It is obvious that patients perceive implantation as a stage before transplantation and they expect further improvement of their life quality. This fact could have a positive effect on patients’ answers.