Incidence of uterine sarcomas in West Bohemia, at the
Department of Gynaecology and Obstetrics, University Hospital
in Pilsen, Czech Republic

J 2017

Incidence of uterine sarcomas in West Bohemia, at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic

KOSŤUN, J., J. BOUDA, P. VLASÁK, A. BARTÁKOVÁ, D. BEREZOVSKIY et. al.

Basic information

Original name

Incidence of uterine sarcomas in West Bohemia, at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic

Authors

KOSŤUN, J. (203 Czech Republic), J. BOUDA (203 Czech Republic), P. VLASÁK (203 Czech Republic), A. BARTÁKOVÁ (203 Czech Republic), D. BEREZOVSKIY (203 Czech Republic), Vít WEINBERGER (203 Czech Republic, guarantor, belonging to the institution) and J. PRESL (203 Czech Republic)

Edition

Česká gynekologie, Praha, Česká lékařská společnost Jana Evangelisty Purkyně, 2017, 1210-7832

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30214 Obstetrics and gynaecology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/17:00100002

Organization unit

Faculty of Medicine

UT WoS

000426974500003

Keywords in English

Cold knife morcellation; Czech Republic; Incidence; Risk factors; Uterine sarcoma

Abstract

V originále

Objective and setting: A retrospective review of women of the West Bohemian population was performed at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic from 1/2005 - 1/2017. Methods: The following data was analysed: patients age, histological type, tumour size, FIGO stage, body mass index, previous irradiation, Tamoxifen USAge, and other possible risk factors. A total number of 20 uterine sarcoma patients were detected in the period from 1/2005 to 1/2015, and these cases were followed until 1/2017. Results: The histological types identified were: leiomyosarcoma in 12 cases, endometrial stromal sarcoma in 7 cases and one case of high-grade undifferentiated uterine sarcoma. This only patient diagnosed with high-grade undifferentiated uterine sarcoma showed distant metastases 12 months after the surgical treatment and died one month later. The whole group of uterine sarcoma patients regardless histological subtype reached two years in 50% of cases, with the median disease-free interval 18 months and the median follow up of 38 months. The diagnosis of sarcoma was already known in 25% of cases from dilatation and curettage histology. There were suspicious sonographic findings suggestive of sarcoma in 10% of cases. Multiparity was associated with 48.2% of endometrial stromal sarcoma cases. The leading clinical symptom was postmenopausal bleeding in 55% of patients. Conclusion: We confirmed uterine sarcomas to be rare malignancies, even in the Czech population with high uterine malignancy incidence. Uterine cold knife morcellation during the vaginal part of laparoscopically assisted vaginal hysterectomy didn't worsen the prognosis of our patients.

Citovat

KOSŤUN, J., J. BOUDA, P. VLASÁK, A. BARTÁKOVÁ, D. BEREZOVSKIY, Vít WEINBERGER and J. PRESL. Incidence of uterine sarcomas in West Bohemia, at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic. Česká gynekologie. Praha: Česká lékařská společnost Jana Evangelisty Purkyně, 2017, vol. 82, No 6, p. 436-442. ISSN 1210-7832.

@article{1408033,
   author = {Kosťun, J. and Bouda, J. and Vlasák, P. and Bartáková, A. and Berezovskiy, D. and Weinberger, Vít and Presl, J.},
   article_location = {Praha},
   article_number = {6},
   keywords = {Cold knife morcellation; Czech Republic; Incidence; Risk factors; Uterine sarcoma},
   language = {eng},
   issn = {1210-7832},
   journal = {Česká gynekologie},
   title = {Incidence of uterine sarcomas in West Bohemia, at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic},
   volume = {82},
   year = {2017}
}

TY  - JOUR
ID  - 1408033
AU  - Kosťun, J. - Bouda, J. - Vlasák, P. - Bartáková, A. - Berezovskiy, D. - Weinberger, Vít - Presl, J.
PY  - 2017
TI  - Incidence of uterine sarcomas in West Bohemia, at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic
JF  - Česká gynekologie
VL  - 82
IS  - 6
SP  - 436-442
EP  - 436-442
PB  - Česká lékařská společnost Jana Evangelisty Purkyně
SN  - 12107832
KW  - Cold knife morcellation
KW  - Czech Republic
KW  - Incidence
KW  - Risk factors
KW  - Uterine sarcoma
N2  - Objective and setting: A retrospective review of women of the West Bohemian population was performed at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic from 1/2005 - 1/2017. Methods: The following data was analysed: patients age, histological type, tumour size, FIGO stage, body mass index, previous irradiation, Tamoxifen USAge, and other possible risk factors. A total number of 20 uterine sarcoma patients were detected in the period from 1/2005 to 1/2015, and these cases were followed until 1/2017. Results: The histological types identified were: leiomyosarcoma in 12 cases, endometrial stromal sarcoma in 7 cases and one case of high-grade undifferentiated uterine sarcoma. This only patient diagnosed with high-grade undifferentiated uterine sarcoma showed distant metastases 12 months after the surgical treatment and died one month later. The whole group of uterine sarcoma patients regardless histological subtype reached two years in 50% of cases, with the median disease-free interval 18 months and the median follow up of 38 months. The diagnosis of sarcoma was already known in 25% of cases from dilatation and curettage histology. There were suspicious sonographic findings suggestive of sarcoma in 10% of cases. Multiparity was associated with 48.2% of endometrial stromal sarcoma cases. The leading clinical symptom was postmenopausal bleeding in 55% of patients. Conclusion: We confirmed uterine sarcomas to be rare malignancies, even in the Czech population with high uterine malignancy incidence. Uterine cold knife morcellation during the vaginal part of laparoscopically assisted vaginal hysterectomy didn't worsen the prognosis of our patients.
ER  -

KOSŤUN, J., J. BOUDA, P. VLASÁK, A. BARTÁKOVÁ, D. BEREZOVSKIY, Vít WEINBERGER and J. PRESL. Incidence of uterine sarcomas in West Bohemia, at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic. \textit{Česká gynekologie}. Praha: Česká lékařská společnost Jana Evangelisty Purkyně, 2017, vol.~82, No~6, p.~436-442. ISSN~1210-7832.

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