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@article{1408033,
author = {Kosťun, J. and Bouda, J. and Vlasák, P. and Bartáková, A. and Berezovskiy, D. and Weinberger, Vít and Presl, J.},
article_location = {Praha},
article_number = {6},
keywords = {Cold knife morcellation; Czech Republic; Incidence; Risk factors; Uterine sarcoma},
language = {eng},
issn = {1210-7832},
journal = {Česká gynekologie},
title = {Incidence of uterine sarcomas in West Bohemia, at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic},
volume = {82},
year = {2017}
}
TY - JOUR
ID - 1408033
AU - Kosťun, J. - Bouda, J. - Vlasák, P. - Bartáková, A. - Berezovskiy, D. - Weinberger, Vít - Presl, J.
PY - 2017
TI - Incidence of uterine sarcomas in West Bohemia, at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic
JF - Česká gynekologie
VL - 82
IS - 6
SP - 436-442
EP - 436-442
PB - Česká lékařská společnost Jana Evangelisty Purkyně
SN - 12107832
KW - Cold knife morcellation
KW - Czech Republic
KW - Incidence
KW - Risk factors
KW - Uterine sarcoma
N2 - Objective and setting: A retrospective review of women of the West Bohemian population was performed at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic from 1/2005 - 1/2017. Methods: The following data was analysed: patients age, histological type, tumour size, FIGO stage, body mass index, previous irradiation, Tamoxifen USAge, and other possible risk factors. A total number of 20 uterine sarcoma patients were detected in the period from 1/2005 to 1/2015, and these cases were followed until 1/2017. Results: The histological types identified were: leiomyosarcoma in 12 cases, endometrial stromal sarcoma in 7 cases and one case of high-grade undifferentiated uterine sarcoma. This only patient diagnosed with high-grade undifferentiated uterine sarcoma showed distant metastases 12 months after the surgical treatment and died one month later. The whole group of uterine sarcoma patients regardless histological subtype reached two years in 50% of cases, with the median disease-free interval 18 months and the median follow up of 38 months. The diagnosis of sarcoma was already known in 25% of cases from dilatation and curettage histology. There were suspicious sonographic findings suggestive of sarcoma in 10% of cases. Multiparity was associated with 48.2% of endometrial stromal sarcoma cases. The leading clinical symptom was postmenopausal bleeding in 55% of patients. Conclusion: We confirmed uterine sarcomas to be rare malignancies, even in the Czech population with high uterine malignancy incidence. Uterine cold knife morcellation during the vaginal part of laparoscopically assisted vaginal hysterectomy didn't worsen the prognosis of our patients.
ER -
KOSŤUN, J., J. BOUDA, P. VLASÁK, A. BARTÁKOVÁ, D. BEREZOVSKIY, Vít WEINBERGER and J. PRESL. Incidence of uterine sarcomas in West Bohemia, at the Department of Gynaecology and Obstetrics, University Hospital in Pilsen, Czech Republic. \textit{Česká gynekologie}. Praha: Česká lékařská společnost Jana Evangelisty Purkyně, 2017, vol.~82, No~6, p.~436-442. ISSN~1210-7832.
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