| BÁNYIOVÁ, Katarína, Milena ČERNÁ, Ondřej MIKEŠ, Klára KOMPRDOVÁ, Anežka SHARMA, Tenzing GYALPO, Pavel ČUPR and Martin SCHERINGER. Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring. Environment International. OXFORD (ENGLAND): PERGAMON-ELSEVIER SCIENCE LTD, 2017, vol. 108, November, p. 1-10. ISSN 0160-4120. Available from: https://dx.doi.org/10.1016/j.envint.2017.07.008. |
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@article{1408676,
author = {Bányiová, Katarína and Černá, Milena and Mikeš, Ondřej and Komprdová, Klára and Sharma, Anežka and Gyalpo, Tenzing and Čupr, Pavel and Scheringer, Martin},
article_location = {OXFORD (ENGLAND)},
article_number = {November},
doi = {http://dx.doi.org/10.1016/j.envint.2017.07.008},
keywords = {Polychlorinated biphenyls; Organochlorine pesticides; Daily intake; Human biomonitoring; Toxicokinetic model; Dietary exposure},
language = {eng},
issn = {0160-4120},
journal = {Environment International},
title = {Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring},
url = {https://www.sciencedirect.com/science/article/pii/S0160412017304312?via%3Dihub},
volume = {108},
year = {2017}
}
TY - JOUR
ID - 1408676
AU - Bányiová, Katarína - Černá, Milena - Mikeš, Ondřej - Komprdová, Klára - Sharma, Anežka - Gyalpo, Tenzing - Čupr, Pavel - Scheringer, Martin
PY - 2017
TI - Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring
JF - Environment International
VL - 108
IS - November
SP - 1-10
EP - 1-10
PB - PERGAMON-ELSEVIER SCIENCE LTD
SN - 01604120
KW - Polychlorinated biphenyls
KW - Organochlorine pesticides
KW - Daily intake
KW - Human biomonitoring
KW - Toxicokinetic model
KW - Dietary exposure
UR - https://www.sciencedirect.com/science/article/pii/S0160412017304312?via%3Dihub
L2 - https://www.sciencedirect.com/science/article/pii/S0160412017304312?via%3Dihub
N2 - Polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) from the group of persistent organic pollutants are detected in human tissues years or even decades after their ban. Exposure to PCBs and OCPs can pose risks to human health. In the present study, we calculated the daily intakes of PCBs and OCPs in the Czech population and investigated the long-term trends of human exposure to POPs. Data on POP concentrations from a 16-year period of breast-milk monitoring were used. A toxicokinetic model with consideration of compound-specific elimination half-lives was used to calculate the mothers' daily intake of PCBs and OCPs representing the intake of POPs by all exposure routes. The calculated intakes were compared with dietary intakes calculated by the Czech National Institute of Public Health. The comparison shows good agreement of both intake estimates with decreasing intake trends of POPs in the Czech population in the time period studied. However, several fluctuations with peaks of higher levels were observed in both datasets which are not typical for the period after the ban of use and production of POPs. The available evidence suggests that the increases in chemical concentrations might be caused by food contamination. The calculated intakes of compounds with longer elimination half-lives, such as higher-chlorinated PCBs, were higher in older mothers. This "memory effect" was already observed in other studies and indicates higher exposure in earlier life periods of the mother. Our results suggest that exposure to POPs is still relevant for the Czech population in the period after the ban of the use and production of POPs (post-ban period), especially via food ingestion, though the intake trends are decreasing. Possible food contamination by POPs in the post-ban period requires further assessment.
ER -
BÁNYIOVÁ, Katarína, Milena ČERNÁ, Ondřej MIKEŠ, Klára KOMPRDOVÁ, Anežka SHARMA, Tenzing GYALPO, Pavel ČUPR and Martin SCHERINGER. Long-term time trends in human intake of POPs in the Czech Republic indicate a need for continuous monitoring. \textit{Environment International}. OXFORD (ENGLAND): PERGAMON-ELSEVIER SCIENCE LTD, 2017, vol.~108, November, p.~1-10. ISSN~0160-4120. Available from: https://dx.doi.org/10.1016/j.envint.2017.07.008.
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