| SHIRAIWA, Manabu, Kayo UEDA, Andrea POZZER, Gerhard LAMMEL, Christopher J. KAMPF, Akihiro FUSHIMI, Shinichi ENAMI, Andrea M. ARANGIO, Janine FROHLICH-NOWOISKY, Yuji FUJITANI, Akiko FURUYAMA, Pascale S. J. LAKEY, Jos LELIEVELD, Kurt LUCAS, Yu MORINO, Ulrich POSCHL, Satoshi TAKAHARNA, Akinori TAKAMI, Haijie TONG, Bettina WEBER, Ayako YOSHINO and Kei SATO. Aerosol Health Effects from Molecular to Global Scales. ENVIRONMENTAL SCIENCE & TECHNOLOGY. WASHINGTON: AMER CHEMICAL SOC, vol. 51, No 23, p. 13545-13567. ISSN 0013-936X. doi:10.1021/acs.est.7b04417. 2017. |
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@article{1409138,
author = {Shiraiwa, Manabu and Ueda, Kayo and Pozzer, Andrea and Lammel, Gerhard and Kampf, Christopher J. and Fushimi, Akihiro and Enami, Shinichi and Arangio, Andrea M. and FrohlichandNowoisky, Janine and Fujitani, Yuji and Furuyama, Akiko and Lakey, Pascale S. J. and Lelieveld, Jos and Lucas, Kurt and Morino, Yu and Poschl, Ulrich and Takaharna, Satoshi and Takami, Akinori and Tong, Haijie and Weber, Bettina and Yoshino, Ayako and Sato, Kei},
article_location = {WASHINGTON},
article_number = {23},
doi = {http://dx.doi.org/10.1021/acs.est.7b04417},
keywords = {SECONDARY ORGANIC AEROSOL; FINE-PARTICULATE MATTER; LONG-TERM EXPOSURE; POLYCYCLIC AROMATIC-HYDROCARBONS},
language = {eng},
issn = {0013-936X},
journal = {ENVIRONMENTAL SCIENCE & TECHNOLOGY},
title = {Aerosol Health Effects from Molecular to Global Scales},
url = {https://pubs.acs.org/doi/10.1021/acs.est.7b04417},
volume = {51},
year = {2017}
}
TY - JOUR
ID - 1409138
AU - Shiraiwa, Manabu - Ueda, Kayo - Pozzer, Andrea - Lammel, Gerhard - Kampf, Christopher J. - Fushimi, Akihiro - Enami, Shinichi - Arangio, Andrea M. - Frohlich-Nowoisky, Janine - Fujitani, Yuji - Furuyama, Akiko - Lakey, Pascale S. J. - Lelieveld, Jos - Lucas, Kurt - Morino, Yu - Poschl, Ulrich - Takaharna, Satoshi - Takami, Akinori - Tong, Haijie - Weber, Bettina - Yoshino, Ayako - Sato, Kei
PY - 2017
TI - Aerosol Health Effects from Molecular to Global Scales
JF - ENVIRONMENTAL SCIENCE & TECHNOLOGY
VL - 51
IS - 23
SP - 13545-13567
EP - 13545-13567
PB - AMER CHEMICAL SOC
SN - 0013936X
KW - SECONDARY ORGANIC AEROSOL
KW - FINE-PARTICULATE MATTER
KW - LONG-TERM EXPOSURE
KW - POLYCYCLIC AROMATIC-HYDROCARBONS
UR - https://pubs.acs.org/doi/10.1021/acs.est.7b04417
L2 - https://pubs.acs.org/doi/10.1021/acs.est.7b04417
N2 - Poor air quality is globally the largest environmental health risk. Epidemiological studies have uncovered clear relationships of gaseous pollutants and particulate matter (PM) with adverse health outcomes, including mortality by cardiovascular and respiratory diseases. Studies of health impacts by aerosols are highly multidisciplinary with a broad range of scales in space and time. We assess recent advances and future challenges regarding aerosol effects on health from molecular to global scales through epidemiological studies, field measurements, health-related properties of PM, and multiphase interactions of oxidants and PM upon respiratory deposition. Global modeling combined with epidemiological exposure response functions indicates that ambient air pollution causes more than four million premature deaths per year. Epidemiological studies usually refer to PM mass concentrations, but some health effects may relate to specific constituents such as bioaerosols, polycyclic aromatic compounds, and transition metals. Various analytical techniques and cellular and molecular assays are applied to assess the redox activity of PM and the formation of reactive oxygen species. Multiphase chemical interactions of lung antioxidants with atmospheric pollutants are crucial to the mechanistic and molecular understanding of oxidative stress upon respiratory deposition. The role of distinct PM components in health impacts and mortality needs to be clarified by integrated research on various spatiotemporal scales for better evaluation and mitigation of aerosol effects on public health in the Anthropocene.
ER -
SHIRAIWA, Manabu, Kayo UEDA, Andrea POZZER, Gerhard LAMMEL, Christopher J. KAMPF, Akihiro FUSHIMI, Shinichi ENAMI, Andrea M. ARANGIO, Janine FROHLICH-NOWOISKY, Yuji FUJITANI, Akiko FURUYAMA, Pascale S. J. LAKEY, Jos LELIEVELD, Kurt LUCAS, Yu MORINO, Ulrich POSCHL, Satoshi TAKAHARNA, Akinori TAKAMI, Haijie TONG, Bettina WEBER, Ayako YOSHINO and Kei SATO. Aerosol Health Effects from Molecular to Global Scales. \textit{ENVIRONMENTAL SCIENCE \&{} TECHNOLOGY}. WASHINGTON: AMER CHEMICAL SOC, vol.~51, No~23, p.~13545-13567. ISSN~0013-936X. doi:10.1021/acs.est.7b04417. 2017.
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