J 2017

Aerosol Health Effects from Molecular to Global Scales

SHIRAIWA, Manabu, Kayo UEDA, Andrea POZZER, Gerhard LAMMEL, Christopher J. KAMPF et. al.

Basic information

Original name

Aerosol Health Effects from Molecular to Global Scales

Authors

SHIRAIWA, Manabu (840 United States of America), Kayo UEDA (392 Japan), Andrea POZZER (276 Germany), Gerhard LAMMEL (276 Germany, guarantor, belonging to the institution), Christopher J. KAMPF (276 Germany), Akihiro FUSHIMI (392 Japan), Shinichi ENAMI (392 Japan), Andrea M. ARANGIO (276 Germany), Janine FROHLICH-NOWOISKY (276 Germany), Yuji FUJITANI (392 Japan), Akiko FURUYAMA (392 Japan), Pascale S. J. LAKEY (840 United States of America), Jos LELIEVELD (276 Germany), Kurt LUCAS (276 Germany), Yu MORINO (392 Japan), Ulrich POSCHL (276 Germany), Satoshi TAKAHARNA (756 Switzerland), Akinori TAKAMI (392 Japan), Haijie TONG (276 Germany), Bettina WEBER (276 Germany), Ayako YOSHINO (392 Japan) and Kei SATO (392 Japan)

Edition

ENVIRONMENTAL SCIENCE & TECHNOLOGY, WASHINGTON, AMER CHEMICAL SOC, 2017, 0013-936X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10511 Environmental sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 6.653

RIV identification code

RIV/00216224:14310/17:00100077

Organization unit

Faculty of Science

UT WoS

000417549500004

Keywords in English

SECONDARY ORGANIC AEROSOL; FINE-PARTICULATE MATTER; LONG-TERM EXPOSURE; POLYCYCLIC AROMATIC-HYDROCARBONS

Tags

Tags

International impact, Reviewed
Změněno: 28/3/2018 09:54, Ing. Nicole Zrilić

Abstract

V originále

Poor air quality is globally the largest environmental health risk. Epidemiological studies have uncovered clear relationships of gaseous pollutants and particulate matter (PM) with adverse health outcomes, including mortality by cardiovascular and respiratory diseases. Studies of health impacts by aerosols are highly multidisciplinary with a broad range of scales in space and time. We assess recent advances and future challenges regarding aerosol effects on health from molecular to global scales through epidemiological studies, field measurements, health-related properties of PM, and multiphase interactions of oxidants and PM upon respiratory deposition. Global modeling combined with epidemiological exposure response functions indicates that ambient air pollution causes more than four million premature deaths per year. Epidemiological studies usually refer to PM mass concentrations, but some health effects may relate to specific constituents such as bioaerosols, polycyclic aromatic compounds, and transition metals. Various analytical techniques and cellular and molecular assays are applied to assess the redox activity of PM and the formation of reactive oxygen species. Multiphase chemical interactions of lung antioxidants with atmospheric pollutants are crucial to the mechanistic and molecular understanding of oxidative stress upon respiratory deposition. The role of distinct PM components in health impacts and mortality needs to be clarified by integrated research on various spatiotemporal scales for better evaluation and mitigation of aerosol effects on public health in the Anthropocene.