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@article{1409685,
author = {Muncke, Jane and Backhaus, Thomas and Geueke, Birgit and Maffini, Maricel V. and Martin, Olwenn Viviane and Myers, John Peterson and Soto, Ana M. and Trasande, Leonardo and Trier, Xenia and Scheringer, Martin},
article_number = {9},
doi = {http://dx.doi.org/10.1289/EHP644},
keywords = {ENDOCRINE-DISRUPTING CHEMICALS; PACKAGING MATERIALS; MASS-SPECTROMETRY; SAFETY ASSESSMENT; SUBSTANCES; EXPOSURE; MIGRATION; QUANTIFICATION; ENVIRONMENT; THRESHOLD},
language = {eng},
issn = {0091-6765},
journal = {ENVIRONMENTAL HEALTH PERSPECTIVES},
title = {Scientific Challenges in the Risk Assessment of Food Contact Materials},
url = {https://ehp.niehs.nih.gov/EHP644/},
volume = {125},
year = {2017}
}
TY - JOUR
ID - 1409685
AU - Muncke, Jane - Backhaus, Thomas - Geueke, Birgit - Maffini, Maricel V. - Martin, Olwenn Viviane - Myers, John Peterson - Soto, Ana M. - Trasande, Leonardo - Trier, Xenia - Scheringer, Martin
PY - 2017
TI - Scientific Challenges in the Risk Assessment of Food Contact Materials
JF - ENVIRONMENTAL HEALTH PERSPECTIVES
VL - 125
IS - 9
SP - "095001-1"-"095001-9"
EP - "095001-1"-"095001-9"
PB - Public Health Services, US Dept of Health and Human Services
SN - 00916765
KW - ENDOCRINE-DISRUPTING CHEMICALS
KW - PACKAGING MATERIALS
KW - MASS-SPECTROMETRY
KW - SAFETY ASSESSMENT
KW - SUBSTANCES
KW - EXPOSURE
KW - MIGRATION
KW - QUANTIFICATION
KW - ENVIRONMENT
KW - THRESHOLD
UR - https://ehp.niehs.nih.gov/EHP644/
L2 - https://ehp.niehs.nih.gov/EHP644/
N2 - BACKGROUND: Food contact articles (FCAs) are manufactured from food contact materials (FCMs) that include plastics, paper, metal, glass, and printing inks. Chemicals can migrate from FCAs into food during storage, processing, and transportation. Food contact materials' safety is evaluated using chemical risk assessment (RA). Several challenges to the RA of FCAs exist. OBJECTIVES: We review regulatory requirements for RA of FCMs in the United States and Europe, identify gaps in RA, and highlight opportunities for improving the protection of public health. We intend to initiate a discussion in the wider scientific community to enhance the safety of food contact articles. DISCUSSION: Based on our evaluation of the evidence, we conclude that current regulations are insufficient for addressing chemical exposures from FCAs. RA currently focuses on monomers and additives used in the manufacture of products, but it does not cover all substances formed in the production processes. Several factors hamper effective RA for many FCMs, including a lack of information on chemical identity, inadequate assessment of hazardous properties, and missing exposure data. Companies make decisions about the safety of some food contact chemicals (FCCS) without review by public authorities. Some chemical migration limits cannot he enforced because analytical standards arc unavailable. CONCLUSION: We think that exposures to hazardous substances migrating from FCAs require more attention. We recommend a) limiting the number and types of chemicals authorized for manufacture and b) developing novel approaches for assessing the safety of chemicals in FCAs, including unidentified chemicals that form during or after production.
ER -
MUNCKE, Jane, Thomas BACKHAUS, Birgit GEUEKE, Maricel V. MAFFINI, Olwenn Viviane MARTIN, John Peterson MYERS, Ana M. SOTO, Leonardo TRASANDE, Xenia TRIER and Martin SCHERINGER. Scientific Challenges in the Risk Assessment of Food Contact Materials. \textit{ENVIRONMENTAL HEALTH PERSPECTIVES}. Public Health Services, US Dept of Health and Human Services, 2017, vol.~125, No~9, p.~''095001-1''-''095001-9'', 9 pp. ISSN~0091-6765. Available from: https://dx.doi.org/10.1289/EHP644.
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