J 2017

Critical assessment of the research outcomes of European birth cohorts: linking environmental factors with non-communicable diseases

PILER, Pavel, Vít KANDRNAL and Luděk BLÁHA

Basic information

Original name

Critical assessment of the research outcomes of European birth cohorts: linking environmental factors with non-communicable diseases

Authors

PILER, Pavel (203 Czech Republic, belonging to the institution), Vít KANDRNAL (203 Czech Republic, belonging to the institution) and Luděk BLÁHA (203 Czech Republic, guarantor, belonging to the institution)

Edition

Public Health, LONDON, W B SAUNDERS CO LTD, 2017, 0033-3506

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30304 Public and environmental health

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 1.441

RIV identification code

RIV/00216224:14310/17:00100221

Organization unit

Faculty of Science

UT WoS

000399629500022

Keywords in English

European birth cohorts; Study design; Research outcomes; Non-communicable diseases

Tags

Tags

International impact, Reviewed
Změněno: 30/3/2018 22:40, Ing. Nicole Zrilić

Abstract

V originále

Objectives: The objective of this review paper was to stimulate collaborative discussions toward the development of a general concept of an open source protocol for a feasible and efficient longitudinal birth cohort study exploring non-communicable diseases (NCDs), their multifactorial etiology and relations between various risk factors. Study design: The present paper systematically reviews the design of existing birth cohorts in Europe containing environmental exposure data, and assesses a quantity and quality of their research outcomes as their potential to be an effective tool for studying non communicable diseases and their risk factors. Methods: European birth cohorts with more than 3000 participants have been included in the study. A total number of scientific papers published in the internationally recognized journals and their impact factors and citation records were evaluated for all cohorts as surrogates for their efficiency to contribute to NCDs understanding and thus their prevention. Results: The birth cohorts contributing most significantly to the NCD understanding shared common features: (i) study size between 10,000 and 15,000 mother-child pairs; (ii) repeated assessment of children from prenatal into adulthood; and (iii) availability of biological samples. Smaller cohorts and cohorts with a specific focus generated a lower number of publications; however, these often received considerably a higher number of citations. Conclusions: General cohort studies with 10,000-15,000 mother child pairs allow a broader context interpretation, publish a higher number of articles, and often lead to the formation of infrastructures for 'spin-off (nested) studies'.

Links

LM2015051, research and development project
Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX RI)
Investor: Ministry of Education, Youth and Sports of the CR
LO1214, research and development project
Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX)
Investor: Ministry of Education, Youth and Sports of the CR
MUNI/M/1075/2013, interní kód MU
Name: CELSPAC: Central European Longitudinal Study of Pregnacy and Childhood (Acronym: CELSPAC)
Investor: Masaryk University, INTERDISCIPLINARY - Interdisciplinary research projects