R 2017

NewProt 1.0

SCHWARTE, A., M. GENZ, L. SKALDEN, A. NOBILI, C. VICKERS et. al.

Basic information

Original name

NewProt 1.0

Authors

SCHWARTE, A. (276 Germany), M. GENZ (276 Germany), L. SKALDEN (276 Germany), A. NOBILI (276 Germany), C. VICKERS (276 Germany), O. MELSE (276 Germany), R. KUIPERS (528 Netherlands), H. JOOSTEN (528 Netherlands), Jan ŠTOURAČ (203 Czech Republic, belonging to the institution), Jaroslav BENDL (203 Czech Republic, belonging to the institution), J. BLACK (528 Netherlands), P. HAASE (276 Germany), C. BAAKMAN (528 Netherlands), Jiří DAMBORSKÝ (203 Czech Republic, guarantor, belonging to the institution), Uwe BORNSCHEUER (276 Germany), G. VRIEND (528 Netherlands) and H. VENSELAAR (528 Netherlands)

Edition

2017

Other information

Language

English

Type of outcome

Software

Field of Study

10201 Computer sciences, information science, bioinformatics

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14310/17:00100413

Organization unit

Faculty of Science

Keywords in English

mutant analysis; portal; protein design; protein engineering; web server

Technical parameters

licenční smlouva není
Změněno: 19/3/2018 12:27, prof. Mgr. Jiří Damborský, Dr.

Abstract

V originále

The NewProt protein engineering portal is a one-stop-shop for in silico protein engineering. It gives access to a large number of servers that compute a wide variety of protein structure characteristics supporting work on the modification of proteins through the introduction of (multiple) point mutations. The results can be inspected through multiple visualizers. The HOPE software is included to indicate mutations with possible undesired side effects. The Hotspot Wizard software is embedded for the design of mutations that modify a proteins’ activity, specificity, or stability. The NewProt portal is freely accessible at http://newprot.cmbi.umcn.nl/ and http://newprot.fluidops.net/.