LANDA, Leoš, Jan JUŘICA, Jiri SLIVA, Monika PECHACKOVA and Regina DEMLOVÁ. Medical cannabis in the treatment of cancer pain and spastic conditions and options of drug delivery in clinical practice. Biomedical Papers, Olomouc: Palacky University. Olomouc: Palacky University, 2018, vol. 162, No 1, p. 18-25. ISSN 1213-8118. Available from: https://dx.doi.org/10.5507/bp.2018.007.
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Basic information
Original name Medical cannabis in the treatment of cancer pain and spastic conditions and options of drug delivery in clinical practice
Name in Czech Lékařské konopí v terapii nádorové bolesti a spastických stavů a možnosti jeho podání v klinické praxi
Authors LANDA, Leoš (203 Czech Republic, belonging to the institution), Jan JUŘICA (203 Czech Republic, belonging to the institution), Jiri SLIVA (203 Czech Republic, guarantor), Monika PECHACKOVA (203 Czech Republic) and Regina DEMLOVÁ (203 Czech Republic, belonging to the institution).
Edition Biomedical Papers, Olomouc: Palacky University, Olomouc, Palacky University, 2018, 1213-8118.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.141
RIV identification code RIV/00216224:14110/18:00100866
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.5507/bp.2018.007
UT WoS 000428951000003
Keywords (in Czech) konopí; bolest; rakovina; křeč; roztroušená skleróza; mechanizmus účinku; THC; kanabinoidy
Keywords in English cannabis; pain; cancer; spasms; multiple sclerosis; mechanism of action; THC; cannabinoids
Tags 14110516, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 26/4/2021 13:44.
Abstract
The use of cannabis for medical purposes has been recently legalised in many countries including the Czech Republic. As a result, there is increased interest on the part of physicians and patients in many aspects of its application. This mini review briefly covers the main active substances of the cannabis plant and mechanisms of action. It focuses on two conditions, cancer pain and spasticity in multiple sclerosis, where its effects are well-documented. A comprehensive overview of a few cannabis-based products and the basic pharmacokinetics of marijuana's constituents follows. The review concludes with an outline for preparing cannabis (dried inflorescence) containing drug dosage forms that can be produced in a hospital pharmacy.
Abstract (in Czech)
Článek se zabývá hlavními aktivními látkami konopí a mechanizmy jejich účinku. Zaměřuje se zejména na nádorovou bolest a roztroušenou sklerózu, kde jsou účinky konopí dobře zdokumentovány. Následuje přehled přípravků obsahujících konopí a základní farmakokinetika složek marihuany. Rewiev je zakončeno popisem přípravy lékových forem obsahujících konopí (suché květenství), které mohou být vyrobeny v nemocniční lékárně.
Links
GA16-06106S, research and development projectName: Vysoce efektivní systém založený na kapilární elektroforéze pro screening inhibitorů beta-sekretázy jako terapeutického cíle pro Alzheimerovu chorobu (Acronym: Alzheimer)
Investor: Czech Science Foundation
LM2015090, research and development projectName: Český národní uzel Evropské sítě infrastruktur klinického výzkumu (Acronym: CZECRIN)
Investor: Ministry of Education, Youth and Sports of the CR
90089, large research infrastructuresName: BBMRI-CZ II
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