Detailed Information on Publication Record
2018
Medical cannabis in the treatment of cancer pain and spastic conditions and options of drug delivery in clinical practice
LANDA, Leoš, Jan JUŘICA, Jiri SLIVA, Monika PECHACKOVA, Regina DEMLOVÁ et. al.Basic information
Original name
Medical cannabis in the treatment of cancer pain and spastic conditions and options of drug delivery in clinical practice
Name in Czech
Lékařské konopí v terapii nádorové bolesti a spastických stavů a možnosti jeho podání v klinické praxi
Authors
LANDA, Leoš (203 Czech Republic, belonging to the institution), Jan JUŘICA (203 Czech Republic, belonging to the institution), Jiri SLIVA (203 Czech Republic, guarantor), Monika PECHACKOVA (203 Czech Republic) and Regina DEMLOVÁ (203 Czech Republic, belonging to the institution)
Edition
Biomedical Papers, Olomouc: Palacky University, Olomouc, Palacky University, 2018, 1213-8118
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30104 Pharmacology and pharmacy
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 1.141
RIV identification code
RIV/00216224:14110/18:00100866
Organization unit
Faculty of Medicine
UT WoS
000428951000003
Keywords (in Czech)
konopí; bolest; rakovina; křeč; roztroušená skleróza; mechanizmus účinku; THC; kanabinoidy
Keywords in English
cannabis; pain; cancer; spasms; multiple sclerosis; mechanism of action; THC; cannabinoids
Tags
International impact, Reviewed
Změněno: 26/4/2021 13:44, Mgr. Tereza Miškechová
V originále
The use of cannabis for medical purposes has been recently legalised in many countries including the Czech Republic. As a result, there is increased interest on the part of physicians and patients in many aspects of its application. This mini review briefly covers the main active substances of the cannabis plant and mechanisms of action. It focuses on two conditions, cancer pain and spasticity in multiple sclerosis, where its effects are well-documented. A comprehensive overview of a few cannabis-based products and the basic pharmacokinetics of marijuana's constituents follows. The review concludes with an outline for preparing cannabis (dried inflorescence) containing drug dosage forms that can be produced in a hospital pharmacy.
In Czech
Článek se zabývá hlavními aktivními látkami konopí a mechanizmy jejich účinku. Zaměřuje se zejména na nádorovou bolest a roztroušenou sklerózu, kde jsou účinky konopí dobře zdokumentovány. Následuje přehled přípravků obsahujících konopí a základní farmakokinetika složek marihuany. Rewiev je zakončeno popisem přípravy lékových forem obsahujících konopí (suché květenství), které mohou být vyrobeny v nemocniční lékárně.
Links
| GA16-06106S, research and development project |
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| LM2015090, research and development project |
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| 90089, large research infrastructures |
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