Informační systém MU
HOŘÁK, Martin, Filip ZLÁMAL, Robert ILIEV, Jan KUČERA, Jan CACEK, Lenka SVOBODOVÁ, Zuzana HLAVOŇOVÁ, Tomáš KALINA, Ondřej SLABÝ a Julie BIENERTOVÁ VAŠKŮ. Exercise-induced circulating microRNA changes in athletes in various training scenarios. Plos one. San Francisco: Public Library of Science, 2018, roč. 13, č. 1, s. 1-14. ISSN 1932-6203. doi:10.1371/journal.pone.0191060.
Další formáty:   BibTeX LaTeX RIS
Základní údaje
Originální název Exercise-induced circulating microRNA changes in athletes in various training scenarios
Autoři HOŘÁK, Martin (203 Česká republika, domácí), Filip ZLÁMAL (203 Česká republika, domácí), Robert ILIEV (203 Česká republika, domácí), Jan KUČERA (203 Česká republika, domácí), Jan CACEK (203 Česká republika, domácí), Lenka SVOBODOVÁ (203 Česká republika, domácí), Zuzana HLAVOŇOVÁ (203 Česká republika, domácí), Tomáš KALINA (203 Česká republika, domácí), Ondřej SLABÝ (203 Česká republika, domácí) a Julie BIENERTOVÁ VAŠKŮ (203 Česká republika, garant, domácí).
Vydání Plos one, San Francisco, Public Library of Science, 2018, 1932-6203.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30105 Physiology
Stát vydavatele Spojené státy
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 2.776
Kód RIV RIV/00216224:14110/18:00102799
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.1371/journal.pone.0191060
UT WoS 000422652700028
Klíčová slova anglicky circulating microRNA
Štítky 14110518, EL OK, podil, rivok
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Mgr. Pavla Foltynová, Ph.D., učo 106624. Změněno: 12. 3. 2019 10:15.
Anotace
Background The aim of the study was to compare selected extracellular miRNA levels (miR-16, miR-21, miR-93 and miR-222 with the response to 8-week-long explosive strength training (EXPL), hypertrophic strength training (HYP) and high-intensity interval training (HIIT). Methods 30 young male athletes of white European origin (mean age: 22.5 +/- 4.06 years) recruited at the Faculty of Sports Studies of Masaryk University were enrolled in this study. The study participants were randomly assigned to three possible training scenarios: EXPL, HYP or HITT and participated in 8-week-long program in given arm. Blood plasma samples were collected at the baseline and at week 5 and 8 and anthropometric and physical activity parameters were measured. Pre- and post-intervention characteristics were compared and participants were further evaluated as responders (RES) or non-responders (NRES). RES/NRES status was established for the following characteristics: 300 degrees/s right leg extension (t300), 60 degrees/s right leg extension (t60), isometric extension (IE), vertical jump, isometric extension of the right leg and body fat percentage (BFP). Results No differences in miRNA levels were apparent between the intervention groups at baseline. No statistically significant prediction role was observed using crude univariate stepwise regression model analysis where RES/NRES status for t300, t60, IE, vertical jump and pFM was used as a dependent variable and miR-21, miR-222, miR-16 and miR-93 levels at baseline were used as independent variables. The baseline levels of miR-93 expressed an independent prediction role for responder status based on isometric extension of the right leg (beta estimate 0.76, 95% CI: -0.01; 1.53, p = 0.052). Discussion The results of the study indicate that 8-week-long explosive strength training, hypertrophic strength training and high-intensity interval training regimens are associated with significant changes in miR-16, mir-21, miR-222 and miR-93 levels compared to a baseline in athletic young men.
Návaznosti
EF15_003/0000469, projekt VaVNázev: Cetocoen Plus
Zobrazeno: 19. 3. 2024 10:17