Detailed Information on Publication Record
2018
Die Rolle von kontrastmittelverstärktem „pulse inversion harmonic imaging“ (CEUS) und kontrastmittelverstärkter Computertomographie (CECT) bei der präoperativen Diagnose von renalen Raumforderungen
KLEZL, P., M. KASPAR, J. KLECKA, R. RICHTEROVA, O. STANC et. al.Basic information
Original name
Die Rolle von kontrastmittelverstärktem „pulse inversion harmonic imaging“ (CEUS) und kontrastmittelverstärkter Computertomographie (CECT) bei der präoperativen Diagnose von renalen Raumforderungen
Name (in English)
The role of contrast-enhanced pulse inversion harmonic imaging (CEUS) and contrast-enhanced computed tomography (CECT) in the preoperative diagnosis of renal lesions
Authors
KLEZL, P. (203 Czech Republic), M. KASPAR (203 Czech Republic), J. KLECKA (203 Czech Republic, guarantor), R. RICHTEROVA (203 Czech Republic), O. STANC (203 Czech Republic), A. BURGETOVA (203 Czech Republic), D. FISCHEROVA (203 Czech Republic), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), G. POPKEN (276 Germany) and F. ZATURA (203 Czech Republic)
Edition
Der Urologe : Zeitschrift für klinische und praktische Urologie. Berlin, Springer, 2018, 0340-2592
Other information
Language
German
Type of outcome
Článek v odborném periodiku
Field of Study
30217 Urology and nephrology
Country of publisher
Germany
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 0.550
RIV identification code
RIV/00216224:14110/18:00102801
Organization unit
Faculty of Medicine
UT WoS
000425288100007
Keywords in English
Contrast-enhanced ultrasound; Harmonic imaging; Computed tomography; Renal tumor; Ultrasound
Tags
International impact, Reviewed
Změněno: 9/2/2019 22:07, Soňa Böhmová
V originále
Zielsetzung Präoperative Analyse struktureller und funktioneller Veränderungen renaler Tumoren unter Einsatz von kontrastmittelverstärktem „pulse inversion harmonic imaging“ (CEUS) und kontrastmittelverstärkter Computertomographie (CECT). Material und Methoden Prospektiv wurden Patienten beim Verdacht maligner renaler Läsionen mithilfe von CEUS und CECT unter den Bedingungen des vordefinierten Studienprotokolls untersucht. Alle malignomverdächtigen Nierenläsionen wurden einer histopathologischen Untersuchung unterzogen. Die als benigne gewerteten Läsionen wurden entsprechend dem Studienprotokoll weiterverfolgt. Die Genauigkeit von CEUS und CECT gegenüber der endgültigen Histologie oder den Follow-up-Ergebnissen sowie der statistisch signifikante Unterschied zwischen beiden bildgebenden Techniken wurden berechnet.
In English
Objective. The preoperative assessment of structural and functional changes in renal tumors using contrast-enhanced pulse inversion harmonic imaging (CEUS) and contrast-enhanced computed tomography (CECT). Materials and methods. All consecutive patients referred to two tertiary hospitals for surgery on suspicion of a malignant renal lesion, who had been examined under the predefined study protocol using CEUS and CECT, were prospectively included in the study. All renal lesions suspected of being malignant were subjected to histopathological examination. Lesions expected to be benign were followed up according to the study protocol. The accuracy of CEUS and CECT with the final histology or follow-up results and the statistically significant difference between the two imaging techniques was calculated. Results. Over a period of 3 years (2008-2011), 68 of 93 patients examined met the study criteria. The prevalence of malignant tumors in the study was 72%. Fifty four (79%) patients underwent surgery and had a histologically confirmed renal tumor (clear cell carcinoma 45, urothelial papillocarcinoma 4, angiomyolipoma 1, oncytoma 3, xanthogranulomatous pyelonephritis 1) and 14 (21%) patients underwent regular followup. Specificity, sensitivity and area under the curve (AUC) reached 57.9%, 98% and 0.779 for CEUS and 52.6%, 98% and 0.753 for CECT. Conclusion. The results show that both imaging methods can reliably rule out malignant disease due to absence of enhancement. Taking into consideration that CEUS can be carried out without severe risk or discomfort, it is time to reconsider CEUS as the method of choice for diagnosis, while CECT should be reserved for staging.