DANHOFER, Pavlína, Jana PEJČOCHOVÁ, Ladislav DUŠEK, Ivan REKTOR and Hana OŠLEJŠKOVÁ. The influence of EEG-detected nocturnal centrotemporal discharges on the expression of core symptoms of ADHD in children with benign childhood epilepsy with centrotemporal spikes (BCECTS): A prospective study in a tertiary referral center. EPILEPSY & BEHAVIOR. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018, vol. 79, FEB 2018, p. 75-81. ISSN 1525-5050. Available from: https://dx.doi.org/10.1016/j.yebeh.2017.11.007.
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Basic information
Original name The influence of EEG-detected nocturnal centrotemporal discharges on the expression of core symptoms of ADHD in children with benign childhood epilepsy with centrotemporal spikes (BCECTS): A prospective study in a tertiary referral center
Authors DANHOFER, Pavlína (203 Czech Republic, guarantor, belonging to the institution), Jana PEJČOCHOVÁ (203 Czech Republic, belonging to the institution), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), Ivan REKTOR (203 Czech Republic, belonging to the institution) and Hana OŠLEJŠKOVÁ (203 Czech Republic, belonging to the institution).
Edition EPILEPSY & BEHAVIOR, SAN DIEGO, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018, 1525-5050.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30103 Neurosciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.378
RIV identification code RIV/00216224:14110/18:00102809
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.yebeh.2017.11.007
UT WoS 000426435800013
Keywords in English Benign childhood epilepsy with centrotemporal spikes; BCECTS; ADHD; Attention deficit; Impulsivity; Hyperactivity
Tags 14110127, 14110320, 14119612, EL OK, podil, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 12/3/2019 16:25.
Abstract
Benign childhood epilepsy with centrotemporal spikes (BCECTS) is the most frequent benign focal epilepsy in childhood. Although it is described as a benign epilepsy syndrome, many studies have revealed that a significant number of patients have some degree of neuropsychological impairment. Thirty-two patients with BCECTS aged 6-11 years were included in the study. All patients (without any antiepileptic or psychiatric medication) underwent all-night EEG monitoring and complex neuropsychological testing to diagnose the presence of core symptoms of attention-deficit/hyperactivity disorder (ADHD). The spike index (number of spikes per minute) on awake and asleep EEG, age at seizure onset, family history of epilepsy, and perinatal risks were correlated with the results of neuropsychological testing. Of the 32 patients, 21 patients (65.6%) fulfilled the criteria for ADHD diagnosis. Children who were younger at epilepsy onset demonstrated lower IQ and higher attention deficit (P=0.004) and higher impulsivity (P=0.016). The occurence of epileptiform discharges on nocturnal EEG was positively related to higher attention deficit and higher impulsivity. The findings are discussed in terms of how interictal discharges in the centrotemporal region during sleep affect the development of cognitive functions in children during critical epochs of neuropsychological development. (C) 2017 Elsevier Inc. All rights reserved.
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