The influence of EEG-detected nocturnal centrotemporal
discharges on the expression of core symptoms of ADHD in
children with benign childhood epilepsy with centrotemporal
spikes (BCECTS): A prospective study in a tertiary referral
center

J 2018

The influence of EEG-detected nocturnal centrotemporal discharges on the expression of core symptoms of ADHD in children with benign childhood epilepsy with centrotemporal spikes (BCECTS): A prospective study in a tertiary referral center

DANHOFER, Pavlína, Jana PEJČOCHOVÁ, Ladislav DUŠEK, Ivan REKTOR, Hana OŠLEJŠKOVÁ et. al.

Basic information

Original name

The influence of EEG-detected nocturnal centrotemporal discharges on the expression of core symptoms of ADHD in children with benign childhood epilepsy with centrotemporal spikes (BCECTS): A prospective study in a tertiary referral center

Authors

DANHOFER, Pavlína (203 Czech Republic, guarantor, belonging to the institution), Jana PEJČOCHOVÁ (203 Czech Republic, belonging to the institution), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), Ivan REKTOR (203 Czech Republic, belonging to the institution) and Hana OŠLEJŠKOVÁ (203 Czech Republic, belonging to the institution)

Edition

EPILEPSY & BEHAVIOR, SAN DIEGO, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018, 1525-5050

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.378

RIV identification code

RIV/00216224:14110/18:00102809

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.yebeh.2017.11.007

UT WoS

000426435800013

Keywords in English

Benign childhood epilepsy with centrotemporal spikes; BCECTS; ADHD; Attention deficit; Impulsivity; Hyperactivity

Abstract

V originále

Benign childhood epilepsy with centrotemporal spikes (BCECTS) is the most frequent benign focal epilepsy in childhood. Although it is described as a benign epilepsy syndrome, many studies have revealed that a significant number of patients have some degree of neuropsychological impairment. Thirty-two patients with BCECTS aged 6-11 years were included in the study. All patients (without any antiepileptic or psychiatric medication) underwent all-night EEG monitoring and complex neuropsychological testing to diagnose the presence of core symptoms of attention-deficit/hyperactivity disorder (ADHD). The spike index (number of spikes per minute) on awake and asleep EEG, age at seizure onset, family history of epilepsy, and perinatal risks were correlated with the results of neuropsychological testing. Of the 32 patients, 21 patients (65.6%) fulfilled the criteria for ADHD diagnosis. Children who were younger at epilepsy onset demonstrated lower IQ and higher attention deficit (P=0.004) and higher impulsivity (P=0.016). The occurence of epileptiform discharges on nocturnal EEG was positively related to higher attention deficit and higher impulsivity. The findings are discussed in terms of how interictal discharges in the centrotemporal region during sleep affect the development of cognitive functions in children during critical epochs of neuropsychological development. (C) 2017 Elsevier Inc. All rights reserved.

Citovat

DANHOFER, Pavlína, Jana PEJČOCHOVÁ, Ladislav DUŠEK, Ivan REKTOR and Hana OŠLEJŠKOVÁ. The influence of EEG-detected nocturnal centrotemporal discharges on the expression of core symptoms of ADHD in children with benign childhood epilepsy with centrotemporal spikes (BCECTS): A prospective study in a tertiary referral center. EPILEPSY & BEHAVIOR. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018, vol. 79, FEB 2018, p. 75-81. ISSN 1525-5050. Available from: https://dx.doi.org/10.1016/j.yebeh.2017.11.007.

@article{1418480,
   author = {Danhofer, Pavlína and Pejčochová, Jana and Dušek, Ladislav and Rektor, Ivan and Ošlejšková, Hana},
   article_location = {SAN DIEGO},
   article_number = {FEB 2018},
   doi = {http://dx.doi.org/10.1016/j.yebeh.2017.11.007},
   keywords = {Benign childhood epilepsy with centrotemporal spikes; BCECTS; ADHD; Attention deficit; Impulsivity; Hyperactivity},
   language = {eng},
   issn = {1525-5050},
   journal = {EPILEPSY & BEHAVIOR},
   title = {The influence of EEG-detected nocturnal centrotemporal discharges on the expression of core symptoms of ADHD in children with benign childhood epilepsy with centrotemporal spikes (BCECTS): A prospective study in a tertiary referral center},
   url = {https://www.sciencedirect.com/science/article/pii/S1525505017307801?via%3Dihub},
   volume = {79},
   year = {2018}
}

TY  - JOUR
ID  - 1418480
AU  - Danhofer, Pavlína - Pejčochová, Jana - Dušek, Ladislav - Rektor, Ivan - Ošlejšková, Hana
PY  - 2018
TI  - The influence of EEG-detected nocturnal centrotemporal discharges on the expression of core symptoms of ADHD in children with benign childhood epilepsy with centrotemporal spikes (BCECTS): A prospective study in a tertiary referral center
JF  - EPILEPSY & BEHAVIOR
VL  - 79
IS  - FEB 2018
SP  - 75-81
EP  - 75-81
PB  - ACADEMIC PRESS INC ELSEVIER SCIENCE
SN  - 15255050
KW  - Benign childhood epilepsy with centrotemporal spikes
KW  - BCECTS
KW  - ADHD
KW  - Attention deficit
KW  - Impulsivity
KW  - Hyperactivity
UR  - https://www.sciencedirect.com/science/article/pii/S1525505017307801?via%3Dihub
N2  - Benign childhood epilepsy with centrotemporal spikes (BCECTS) is the most frequent benign focal epilepsy in childhood. Although it is described as a benign epilepsy syndrome, many studies have revealed that a significant number of patients have some degree of neuropsychological impairment. Thirty-two patients with BCECTS aged 6-11 years were included in the study. All patients (without any antiepileptic or psychiatric medication) underwent all-night EEG monitoring and complex neuropsychological testing to diagnose the presence of core symptoms of attention-deficit/hyperactivity disorder (ADHD). The spike index (number of spikes per minute) on awake and asleep EEG, age at seizure onset, family history of epilepsy, and perinatal risks were correlated with the results of neuropsychological testing. Of the 32 patients, 21 patients (65.6%) fulfilled the criteria for ADHD diagnosis. Children who were younger at epilepsy onset demonstrated lower IQ and higher attention deficit (P=0.004) and higher impulsivity (P=0.016). The occurence of epileptiform discharges on nocturnal EEG was positively related to higher attention deficit and higher impulsivity. The findings are discussed in terms of how interictal discharges in the centrotemporal region during sleep affect the development of cognitive functions in children during critical epochs of neuropsychological development. (C) 2017 Elsevier Inc. All rights reserved.
ER  -

DANHOFER, Pavlína, Jana PEJČOCHOVÁ, Ladislav DUŠEK, Ivan REKTOR and Hana OŠLEJŠKOVÁ. The influence of EEG-detected nocturnal centrotemporal discharges on the expression of core symptoms of ADHD in children with benign childhood epilepsy with centrotemporal spikes (BCECTS): A prospective study in a tertiary referral center. \textit{EPILEPSY \&{}amp; BEHAVIOR}. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2018, vol.~79, FEB 2018, p.~75-81. ISSN~1525-5050. Available from: https://dx.doi.org/10.1016/j.yebeh.2017.11.007.

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