J 2018

New echocardiographic parameters in the diagnosis of heart failure with preserved ejection fraction

ŠPINAROVÁ, Monika, Jaroslav MELUZÍN, Helena PODROUŽKOVÁ, Radka ŠTĚPÁNOVÁ, Lenka ŠPINAROVÁ et. al.

Basic information

Original name

New echocardiographic parameters in the diagnosis of heart failure with preserved ejection fraction

Authors

ŠPINAROVÁ, Monika (203 Czech Republic, guarantor, belonging to the institution), Jaroslav MELUZÍN (203 Czech Republic, belonging to the institution), Helena PODROUŽKOVÁ (203 Czech Republic), Radka ŠTĚPÁNOVÁ (203 Czech Republic) and Lenka ŠPINAROVÁ (203 Czech Republic, belonging to the institution)

Edition

International Journal of Cardiovascular Imaging, Dordrecht, Springer, 2018, 1569-5794

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 1.860

RIV identification code

RIV/00216224:14110/18:00102833

Organization unit

Faculty of Medicine

UT WoS

000424890500010

Keywords in English

Heart failure with preserved ejection fraction; Diastolic wall strain; Vortex formation time

Tags

International impact, Reviewed
Změněno: 27/1/2021 12:47, Mgr. Tereza Miškechová

Abstract

V originále

Heart failure with preserved ejection fraction (HFpEF) is a serious clinical disease. The pathophysiology of HFpEF is complex, and specific diagnostic criteria have evolved over time. Limited data are available on the quantification of diastolic function using two-dimensional real-time echocardiography, and a simple parameter has not yet been established. The aim of this work is to evaluate new echocardiographic parameters-the diastolic wall strain of the posterior wall (DWS PW) and the vortex formation time (VFT). Echocardiographic data from 111 subjects with exertional dyspnea and normal left ejection fraction (Group A) and 20 healthy volunteers (Group B) were retrospectively evaluated. In addition to the standard parameters used in the diagnosis of HFpEF, DWS PW and VFT were assessed in all patients. HFpEF was diagnosed in 38 patients with dyspnea (Group A1). The remaining 73 patients did not meet the established criteria for a positive diagnosis of HFpEF (Group A2). We discovered that both observed parameters were significantly lower in patients with HFpEF than in other groups. Multivariate analysis revealed that both DWS PW and VFT independently predicted the presence of HFpEF. DWS PW and VFT are simple parameters in the evaluation of diastolic function and may play a potential role as a part of an integrated approach to the assessment of HFpEF.

Links

LM2015090, research and development project
Name: Český národní uzel Evropské sítě infrastruktur klinického výzkumu (Acronym: CZECRIN)
Investor: Ministry of Education, Youth and Sports of the CR
MUNI/A/1270/2015, interní kód MU
Name: Význam bioptické diagnostiky u nově vzniklé dilatační kardiomyopatie
Investor: Masaryk University, Category A