ŠPINAROVÁ, Monika, Jaroslav MELUZÍN, Helena PODROUŽKOVÁ, Radka ŠTĚPÁNOVÁ and Lenka ŠPINAROVÁ. New echocardiographic parameters in the diagnosis of heart failure with preserved ejection fraction. International Journal of Cardiovascular Imaging. Dordrecht: Springer, 2018, vol. 34, No 2, p. 229-235. ISSN 1569-5794. Available from: https://dx.doi.org/10.1007/s10554-017-1230-z.
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Basic information
Original name New echocardiographic parameters in the diagnosis of heart failure with preserved ejection fraction
Authors ŠPINAROVÁ, Monika (203 Czech Republic, guarantor, belonging to the institution), Jaroslav MELUZÍN (203 Czech Republic, belonging to the institution), Helena PODROUŽKOVÁ (203 Czech Republic), Radka ŠTĚPÁNOVÁ (203 Czech Republic) and Lenka ŠPINAROVÁ (203 Czech Republic, belonging to the institution).
Edition International Journal of Cardiovascular Imaging, Dordrecht, Springer, 2018, 1569-5794.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.860
RIV identification code RIV/00216224:14110/18:00102833
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1007/s10554-017-1230-z
UT WoS 000424890500010
Keywords in English Heart failure with preserved ejection fraction; Diastolic wall strain; Vortex formation time
Tags 14110115, EL OK, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 27/1/2021 12:47.
Abstract
Heart failure with preserved ejection fraction (HFpEF) is a serious clinical disease. The pathophysiology of HFpEF is complex, and specific diagnostic criteria have evolved over time. Limited data are available on the quantification of diastolic function using two-dimensional real-time echocardiography, and a simple parameter has not yet been established. The aim of this work is to evaluate new echocardiographic parameters-the diastolic wall strain of the posterior wall (DWS PW) and the vortex formation time (VFT). Echocardiographic data from 111 subjects with exertional dyspnea and normal left ejection fraction (Group A) and 20 healthy volunteers (Group B) were retrospectively evaluated. In addition to the standard parameters used in the diagnosis of HFpEF, DWS PW and VFT were assessed in all patients. HFpEF was diagnosed in 38 patients with dyspnea (Group A1). The remaining 73 patients did not meet the established criteria for a positive diagnosis of HFpEF (Group A2). We discovered that both observed parameters were significantly lower in patients with HFpEF than in other groups. Multivariate analysis revealed that both DWS PW and VFT independently predicted the presence of HFpEF. DWS PW and VFT are simple parameters in the evaluation of diastolic function and may play a potential role as a part of an integrated approach to the assessment of HFpEF.
Links
LM2015090, research and development projectName: Český národní uzel Evropské sítě infrastruktur klinického výzkumu (Acronym: CZECRIN)
Investor: Ministry of Education, Youth and Sports of the CR
MUNI/A/1270/2015, interní kód MUName: Význam bioptické diagnostiky u nově vzniklé dilatační kardiomyopatie
Investor: Masaryk University, Category A
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