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@article{1419737,
author = {Řiháček, Ivan and Němec, Petr and Řiháček, Michal and Kianička, Bohuslav and Berukstis, Andrius and Caprnda, Martin and Gaspar, Ludovit and Kružliak, Peter and Souček, Miroslav},
article_location = {London},
article_number = {6},
keywords = {hypertension; rheumatoid arthritis; 24-hour ambulatory blood pressure monitoring},
language = {eng},
issn = {1758-4272},
journal = {International Journal of Clinical Rheumatology},
title = {Ambulatory blood pressure monitoring and hypertension related cardiovascular risk in patients with rheumatoid arthritis},
volume = {12},
year = {2017}
}
TY - JOUR
ID - 1419737
AU - Řiháček, Ivan - Němec, Petr - Řiháček, Michal - Kianička, Bohuslav - Berukstis, Andrius - Caprnda, Martin - Gaspar, Ludovit - Kružliak, Peter - Souček, Miroslav
PY - 2017
TI - Ambulatory blood pressure monitoring and hypertension related cardiovascular risk in patients with rheumatoid arthritis
JF - International Journal of Clinical Rheumatology
VL - 12
IS - 6
SP - 142-150
EP - 142-150
PB - Future Medicine Ltd.
SN - 17584272
KW - hypertension
KW - rheumatoid arthritis
KW - 24-hour ambulatory blood pressure monitoring
N2 - Background: To assess hypertension related cardiovascular risk parameters in patients with rheumatoid arthritis. To determine the effect of long-term treatment with corticosteroids, non-steroid antiinflammatory drugs, and methotrexate on diurnal BP variability. Material and methods: 60 patients with clinically stable rheumatoid arthritis and treated hypertension. Casual blood pressure measurement and 24-hour ambulatory blood pressure monitoring. Results: Mean casual systolic blood pressure 139.0 ± 14.6 mmHg, diastolic blood pressure 85.7 ± 6.5 mmHg, and heart rate 74.9 ± 7.2 beats.min-1. Mean 24-hour systolic blood pressure 129.0 ± 12.7 mmHg, diastolic blood pressure 77.6 ± 7.4 mmHg, and heart rate 73.9 ± 8.7 beats.min-1. Mean casual pulse pressure 54.7 ± 15.6 mmHg, and the mean 24-hour ambulatory pulse pressure 50.1 ± 11.0 mmHg. The mean morning surge of systolic blood pressure 35.3 ± 11.00 mmHg. The number of patients with increased short-term variability of their systolic blood pressure using the coefficient of variation 30 (50%). A number of systolic nondippers in the group were treated with corticosteroids and non-steroidal anti-inflammatory drugs 34% and 35%, respectively, and a number of excessive diastolic dippers in the group were treated with methotrexate 49%. Conclusions: Certain hypertension characteristics in patients with rheumatoid arthritis can increase cardiovascular risk: Higher pulse pressure, elevated levels of morning surge of systolic blood pressure, increased short-term 24-hour blood pressure variability, higher number of systolic nondippers treated with corticosteroids and non-steroidal anti-inflammatory drugs, and excessive diastolic dippers treated with methotrexate. In addition increased heart rate may contribute to higher cardiovascular risk.
ER -
ŘIHÁČEK, Ivan, Petr NĚMEC, Michal ŘIHÁČEK, Bohuslav KIANIČKA, Andrius BERUKSTIS, Martin CAPRNDA, Ludovit GASPAR, Peter KRUŽLIAK a Miroslav SOUČEK. Ambulatory blood pressure monitoring and hypertension related cardiovascular risk in patients with rheumatoid arthritis. Online. \textit{International Journal of Clinical Rheumatology}. London: Future Medicine Ltd., 2017, roč.~12, č.~6, s.~142-150. ISSN~1758-4272. [citováno 2024-04-23]
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