Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries

STAŠKOVÁ, Klára, Pavel TOUŠEK, František TOUŠEK, Anna MALÁ, Michael ŽELÍZKO, David HORÁK, Martin SLUKA, Alexandra VODZINSKÁ, Radek JANČAR, Michael ASCHERMANN, Jiří JARKOVSKÝ and Petr WIDIMSKÝ. Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries. Cor et Vasa. AMSTERDAM: ELSEVIER SCIENCE BV, 2018, vol. 60, No 1, p. "E66"-"E69", 4 pp. ISSN 0010-8650. Available from: https://dx.doi.org/10.1016/j.crvasa.2017.02.007.

Basic information

Original name

Trends in the treatment and outcomes of elderly patients with acute coronary syndrome: Results from the CZECH registries

Authors

STAŠKOVÁ, Klára (203 Czech Republic), Pavel TOUŠEK (203 Czech Republic, guarantor), František TOUŠEK (203 Czech Republic), Anna MALÁ (203 Czech Republic), Michael ŽELÍZKO (203 Czech Republic), David HORÁK (203 Czech Republic), Martin SLUKA (203 Czech Republic), Alexandra VODZINSKÁ (203 Czech Republic), Radek JANČAR (203 Czech Republic), Michael ASCHERMANN (203 Czech Republic), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution) and Petr WIDIMSKÝ (203 Czech Republic)

Edition

Cor et Vasa, AMSTERDAM, ELSEVIER SCIENCE BV, 2018, 0010-8650

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/18:00102945

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.crvasa.2017.02.007

UT WoS

000426976600012

Keywords in English

Elderly; Acute coronary syndrome; Treatment strategy; Outcome

Tags

14119612, EL OK, rivok

Tags

International impact, Reviewed

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Abstract

V originále

Background: The number of elderly patients in the population is rapidly increasing, and little is known about how adherence to recommended treatment strategies in elderly patients with acute coronary syndrome (ACS) has changed over time. Aim: To analyze trends in the treatment and outcomes of elderly patients with ACS from two registries conducted in the Czech Republic over 10 years. Methods and results: Data from the CZECH-1 and CZECH-3 registries were used in this study. These registries collected data in autumn 2005 and autumn 2015, and contain data from 1952 and 1754 unselected patients, respectively. All patients had been hospitalized with an initial diagnosis of ACS. There were 490 (25.7%) elderly patients in the CZECH-1 registry and 484 (28.1%) elderly patients in the CZECH-3 registry (p = 0.045) with an average age of 80.6 +/- 4 and 82.1 +/- 5 years (p < 0.001), respectively. ACS was confirmed in 345 (72%) and 352 (73.6%) elderly patients (p = 0.781), respectively. There was higher use of percutaneous coronary intervention (65.2% and 54.8%; p < 0.001), dual antiplatelet treatment, ACE inhibitors, and statins during treatment in the CZECH-3 compared to the CZECH-1 registry. No differences in hospital mortality of elderly patients with confirmed ACS were observed between registries (8.2% vs. 10.4%; p = 0.790). Conclusion: The proportion of patients with ACS that are elderly is increasing along with their increasing average age. Adherence to guideline-recommended therapy in this subgroup of patients has improved over time, but hospital mortality remains unchanged. (c) 2017 The Czech Society of Cardiology. Published by Elsevier Sp. z o. o. All rights reserved.