KUNOVSKÝ, Lumír, Zdeněk KALA, Roman SVATOŇ, Petr MORAVČÍK, Jan MAZANEC, Jakub HUSTÝ and Vladimír PROCHÁZKA. Mucinous cystic neoplasm of the liver or intraductal papillary mucinous neoplasm of the bile duct? A case report and a review of literature. Annals of hepatology. Mexico City: Ediciones Medicina y Cultura, 2018, vol. 17, No 3, p. 519-524. ISSN 1665-2681. Available from: https://dx.doi.org/10.5604/01.3001.0011.7397.
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Basic information
Original name Mucinous cystic neoplasm of the liver or intraductal papillary mucinous neoplasm of the bile duct? A case report and a review of literature
Authors KUNOVSKÝ, Lumír (203 Czech Republic, guarantor, belonging to the institution), Zdeněk KALA (203 Czech Republic, belonging to the institution), Roman SVATOŇ (703 Slovakia, belonging to the institution), Petr MORAVČÍK (203 Czech Republic, belonging to the institution), Jan MAZANEC (203 Czech Republic, belonging to the institution), Jakub HUSTÝ (203 Czech Republic, belonging to the institution) and Vladimír PROCHÁZKA (203 Czech Republic, belonging to the institution).
Edition Annals of hepatology, Mexico City, Ediciones Medicina y Cultura, 2018, 1665-2681.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30219 Gastroenterology and hepatology
Country of publisher Mexico
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.895
RIV identification code RIV/00216224:14110/18:00102959
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.5604/01.3001.0011.7397
UT WoS 000460748500021
Keywords in English Biliary intraductal papillary mucinous neoplasm; Hepatic mucinous cystic neoplasm; Liver lesions; Ovarian-like stroma; Surgery
Tags 14110213, 14110216, 14110223, 14110230, EL OK, rivok
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 26/4/2019 09:19.
Abstract
Mucinous cystic neoplasm of the liver (MCN-L) and intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) are diagnoses that were classified by the World Health Organization in 2010 as mucin-producing bile duct tumors of the hepatobiliary system. The preoperative differential diagnosis between these two entities is difficult; the presence of a communication with the bile duct is usually considered as a typical sign of IPMN-B. However, the presence of an ovarian-like stroma (OLS) has been established to define the diagnosis of MCN-L. We present the case of a 33-year-old woman with a rapid progression of a cystic tumor of the liver. In 2 years, the lesion increased from 27 to 64 mm and a dilation of the left hepatic duct appeared. Percutaneous transhepatic drainage with a biopsy was performed. No malignant cells were found on biopsy. Because of the rapid progression of the cystic tumor and unclear malignant potential, left hemihepatectomy was performed. Even though tumor masses were present in the biliary duct, on the basis of the presence of OLS, histology finally confirmed MCN-L with intermediate-grade intraepithelial dysplasia to high-grade intraepithelial dysplasia. The patient is currently under oncologic follow-up with no signs of recurrence of the disease. We present a rare case where MCN-L caused a dilation of the left hepatic duct, a sign that is usually a characteristic of IPMN-B.
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