Mucinous cystic neoplasm of the liver or intraductal papillary
mucinous neoplasm of the bile duct? A case report and a review
of literature

J 2018

Mucinous cystic neoplasm of the liver or intraductal papillary mucinous neoplasm of the bile duct? A case report and a review of literature

KUNOVSKÝ, Lumír, Zdeněk KALA, Roman SVATOŇ, Petr MORAVČÍK, Jan MAZANEC et. al.

Basic information

Original name

Mucinous cystic neoplasm of the liver or intraductal papillary mucinous neoplasm of the bile duct? A case report and a review of literature

Authors

KUNOVSKÝ, Lumír (203 Czech Republic, guarantor, belonging to the institution), Zdeněk KALA (203 Czech Republic, belonging to the institution), Roman SVATOŇ (703 Slovakia, belonging to the institution), Petr MORAVČÍK (203 Czech Republic, belonging to the institution), Jan MAZANEC (203 Czech Republic, belonging to the institution), Jakub HUSTÝ (203 Czech Republic, belonging to the institution) and Vladimír PROCHÁZKA (203 Czech Republic, belonging to the institution)

Edition

Annals of hepatology, Mexico City, Ediciones Medicina y Cultura, 2018, 1665-2681

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30219 Gastroenterology and hepatology

Country of publisher

Mexico

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.895

RIV identification code

RIV/00216224:14110/18:00102959

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.5604/01.3001.0011.7397

UT WoS

000460748500021

Keywords in English

Biliary intraductal papillary mucinous neoplasm; Hepatic mucinous cystic neoplasm; Liver lesions; Ovarian-like stroma; Surgery

Abstract

V originále

Mucinous cystic neoplasm of the liver (MCN-L) and intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) are diagnoses that were classified by the World Health Organization in 2010 as mucin-producing bile duct tumors of the hepatobiliary system. The preoperative differential diagnosis between these two entities is difficult; the presence of a communication with the bile duct is usually considered as a typical sign of IPMN-B. However, the presence of an ovarian-like stroma (OLS) has been established to define the diagnosis of MCN-L. We present the case of a 33-year-old woman with a rapid progression of a cystic tumor of the liver. In 2 years, the lesion increased from 27 to 64 mm and a dilation of the left hepatic duct appeared. Percutaneous transhepatic drainage with a biopsy was performed. No malignant cells were found on biopsy. Because of the rapid progression of the cystic tumor and unclear malignant potential, left hemihepatectomy was performed. Even though tumor masses were present in the biliary duct, on the basis of the presence of OLS, histology finally confirmed MCN-L with intermediate-grade intraepithelial dysplasia to high-grade intraepithelial dysplasia. The patient is currently under oncologic follow-up with no signs of recurrence of the disease. We present a rare case where MCN-L caused a dilation of the left hepatic duct, a sign that is usually a characteristic of IPMN-B.

Citovat

KUNOVSKÝ, Lumír, Zdeněk KALA, Roman SVATOŇ, Petr MORAVČÍK, Jan MAZANEC, Jakub HUSTÝ and Vladimír PROCHÁZKA. Mucinous cystic neoplasm of the liver or intraductal papillary mucinous neoplasm of the bile duct? A case report and a review of literature. Annals of hepatology. Mexico City: Ediciones Medicina y Cultura, 2018, vol. 17, No 3, p. 519-524. ISSN 1665-2681. Available from: https://dx.doi.org/10.5604/01.3001.0011.7397.

@article{1420065,
   author = {Kunovský, Lumír and Kala, Zdeněk and Svatoň, Roman and Moravčík, Petr and Mazanec, Jan and Hustý, Jakub and Procházka, Vladimír},
   article_location = {Mexico City},
   article_number = {3},
   doi = {http://dx.doi.org/10.5604/01.3001.0011.7397},
   keywords = {Biliary intraductal papillary mucinous neoplasm; Hepatic mucinous cystic neoplasm; Liver lesions; Ovarian-like stroma; Surgery},
   language = {eng},
   issn = {1665-2681},
   journal = {Annals of hepatology},
   title = {Mucinous cystic neoplasm of the liver or intraductal papillary mucinous neoplasm of the bile duct? A case report and a review of literature},
   volume = {17},
   year = {2018}
}

TY  - JOUR
ID  - 1420065
AU  - Kunovský, Lumír - Kala, Zdeněk - Svatoň, Roman - Moravčík, Petr - Mazanec, Jan - Hustý, Jakub - Procházka, Vladimír
PY  - 2018
TI  - Mucinous cystic neoplasm of the liver or intraductal papillary mucinous neoplasm of the bile duct? A case report and a review of literature
JF  - Annals of hepatology
VL  - 17
IS  - 3
SP  - 519-524
EP  - 519-524
PB  - Ediciones Medicina y Cultura
SN  - 16652681
KW  - Biliary intraductal papillary mucinous neoplasm
KW  - Hepatic mucinous cystic neoplasm
KW  - Liver lesions
KW  - Ovarian-like stroma
KW  - Surgery
N2  - Mucinous cystic neoplasm of the liver (MCN-L) and intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) are diagnoses that were classified by the World Health Organization in 2010 as mucin-producing bile duct tumors of the hepatobiliary system. The preoperative differential diagnosis between these two entities is difficult; the presence of a communication with the bile duct is usually considered as a typical sign of IPMN-B. However, the presence of an ovarian-like stroma (OLS) has been established to define the diagnosis of MCN-L. We present the case of a 33-year-old woman with a rapid progression of a cystic tumor of the liver. In 2 years, the lesion increased from 27 to 64 mm and a dilation of the left hepatic duct appeared. Percutaneous transhepatic drainage with a biopsy was performed. No malignant cells were found on biopsy. Because of the rapid progression of the cystic tumor and unclear malignant potential, left hemihepatectomy was performed. Even though tumor masses were present in the biliary duct, on the basis of the presence of OLS, histology finally confirmed MCN-L with intermediate-grade intraepithelial dysplasia to high-grade intraepithelial dysplasia. The patient is currently under oncologic follow-up with no signs of recurrence of the disease. We present a rare case where MCN-L caused a dilation of the left hepatic duct, a sign that is usually a characteristic of IPMN-B.
ER  -

KUNOVSKÝ, Lumír, Zdeněk KALA, Roman SVATOŇ, Petr MORAVČÍK, Jan MAZANEC, Jakub HUSTÝ and Vladimír PROCHÁZKA. Mucinous cystic neoplasm of the liver or intraductal papillary mucinous neoplasm of the bile duct? A case report and a review of literature. \textit{Annals of hepatology}. Mexico City: Ediciones Medicina y Cultura, 2018, vol.~17, No~3, p.~519-524. ISSN~1665-2681. Available from: https://dx.doi.org/10.5604/01.3001.0011.7397.

Detailed Information on Publication Record