The research paper extends the previous knowledge on destination management in the Czech Republic. It gives detailed understanding of mutual interactions in the socio-cultural and economic context. The object of the research is network relations established due to the participation in a tourism product. The aim is to identify the role of small and medium-sized enterprises in destination development from the network perspective in the conditions of the Czech Republic. The applied network analysis provides relevant results to describe collaborative relationships among stakeholders and the luck of governance in destinations of the Czech Republic.