| LATTA, Peter, Z. STARCUK, M.L.H. GRUWEL, Barbora LATTOVA, Petra LATTOVA, Pavel ŠTOURAČ and Boguslaw TOMANEK. Influence of k-space trajectory corrections on proton density mapping with ultrashort echo time imaging: Application for imaging of short T2 components in white matter. MAGNETIC RESONANCE IMAGING. NEW YORK: ELSEVIER SCIENCE INC, 2018, vol. 51, SEP, p. 87-95. ISSN 0730-725X. Available from: https://dx.doi.org/10.1016/j.mri.2018.04.020. |
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@article{1443118,
author = {Latta, Peter and Starcuk, Z. and Gruwel, M.L.H. and Lattova, Barbora and Lattova, Petra and Štourač, Pavel and Tomanek, Boguslaw},
article_location = {NEW YORK},
article_number = {SEP},
doi = {http://dx.doi.org/10.1016/j.mri.2018.04.020},
keywords = {Ultrashort T2; Gradient system imperfections; Ultrashort echo time (UTE); Quantitative MRI},
language = {eng},
issn = {0730-725X},
journal = {MAGNETIC RESONANCE IMAGING},
title = {Influence of k-space trajectory corrections on proton density mapping with ultrashort echo time imaging: Application for imaging of short T2 components in white matter},
url = {https://www.sciencedirect.com/science/article/pii/S0730725X18301036?via%3Dihub},
volume = {51},
year = {2018}
}
TY - JOUR
ID - 1443118
AU - Latta, Peter - Starcuk, Z. - Gruwel, M.L.H. - Lattova, Barbora - Lattova, Petra - Štourač, Pavel - Tomanek, Boguslaw
PY - 2018
TI - Influence of k-space trajectory corrections on proton density mapping with ultrashort echo time imaging: Application for imaging of short T2 components in white matter
JF - MAGNETIC RESONANCE IMAGING
VL - 51
IS - SEP
SP - 87-95
EP - 87-95
PB - ELSEVIER SCIENCE INC
SN - 0730725X
KW - Ultrashort T2
KW - Gradient system imperfections
KW - Ultrashort echo time (UTE)
KW - Quantitative MRI
UR - https://www.sciencedirect.com/science/article/pii/S0730725X18301036?via%3Dihub
N2 - Purpose: To evaluate the impact of MR gradient system imperfections and limitations for the quantitative mapping of short T2* signals performed by ultrashort echo time (UTE) acquisition approach. Materials and methods: The measurement of short T2* signals from a phantom and a healthy volunteer study (8 subjects of average age 28 4 years) were performed on a 3T scanner. The characteristics of the gradient system were obtained using calibration method performed directly on the measured subject or phantom. This information was used to calculate the actual sampling trajectory with the help of a parametric eddy current model. The actual sample positions were used to reconstruct corrected images and compared with uncorrected data. Results: Comparison of both approaches, i.e., without and with correction of k-space sampling trajectories revealed substantial improvement when correction was applied. The phantom experiments demonstrate substantial in-plane signal intensity variations for uncorrected sampling trajectories. In the case of the volunteer study, this led to significant differences in relative proton density (RPD) estimation between the uncorrected and corrected data (P = 0.0117 by Wilcoxon matched-pairs test) and provides for about 15% higher values for short T2* components of white matter (WM) in the case of uncorrected images. Conclusion: The imperfection of the applied gradients could induce errors in k-space data sampling which further propagates into the fidelity of the UTE images and jeopardizes precision of quantification. However, the study proved that measurement of gradient errors together with correction of sample positions can contribute to increased accuracy and unbiased characterization of short T2* signals.
ER -
LATTA, Peter, Z. STARCUK, M.L.H. GRUWEL, Barbora LATTOVA, Petra LATTOVA, Pavel ŠTOURAČ and Boguslaw TOMANEK. Influence of k-space trajectory corrections on proton density mapping with ultrashort echo time imaging: Application for imaging of short T2 components in white matter. \textit{MAGNETIC RESONANCE IMAGING}. NEW YORK: ELSEVIER SCIENCE INC, 2018, vol.~51, SEP, p.~87-95. ISSN~0730-725X. Available from: https://dx.doi.org/10.1016/j.mri.2018.04.020.
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