Enhanced bioactivity of electrospun PCL and PLLA scaffolds
blended with amino-phosphazene

J 2018

Enhanced bioactivity of electrospun PCL and PLLA scaffolds blended with amino-phosphazene

SEDLÁKOVÁ, Veronika, Zbyněk VORÁČ, Josef JAROŠ, Radka KOPECKÁ, Michaela KLOUČKOVÁ et. al.

Basic information

Original name

Enhanced bioactivity of electrospun PCL and PLLA scaffolds blended with amino-phosphazene

Authors

SEDLÁKOVÁ, Veronika (203 Czech Republic, belonging to the institution), Zbyněk VORÁČ (203 Czech Republic, belonging to the institution), Josef JAROŠ (203 Czech Republic, belonging to the institution), Radka KOPECKÁ (203 Czech Republic, belonging to the institution), Michaela KLOUČKOVÁ (203 Czech Republic, belonging to the institution), Michal SVOBODA (203 Czech Republic, belonging to the institution), Libor STREIT (203 Czech Republic, belonging to the institution), Jana DUMKOVÁ (203 Czech Republic, belonging to the institution), Kateřina VAŠÍČKOVÁ (203 Czech Republic, belonging to the institution), Milan ALBERTI (203 Czech Republic, belonging to the institution) and Aleš HAMPL (203 Czech Republic, guarantor, belonging to the institution)

Edition

Materials Letters, Amsterdam, Elsevier Science, 2018, 0167-577X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30404 Biomaterials

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.019

RIV identification code

RIV/00216224:14110/18:00103938

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.matlet.2018.06.023

UT WoS

000439045500086

Keywords in English

Phosphazene; Amino; Electrospinning; Biomaterials; Biomimetic; Morphology

Abstract

V originále

Here we report for the first time that blending hexaamino-cyclo-triphosphazene with either poly-epsilon-caprolactone or poly-L-lactic acid enables the generation of blended electrospun scaffolds with enhanced bioactivities. These hexaamino-cyclo-triphosphazene-modified fibers significantly promote cell adhesion, spreading, metabolism, and proliferation. In addition to that we also report more efficient hexaaminocyclo-triphosphazene synthesis with a higher yield and purity.

Links

LD15144, research and development project

Name: Buněčné a nebuněčné základy pro regeneraci kostí a zubů (Acronym: TissueENG)

Investor: Ministry of Education, Youth and Sports of the CR

MUNI/A/1369/2016, interní kód MU

Name: Zdroje pro tkáňové inženýrství 7 (Acronym: TissueENG 7)

Investor: Masaryk University, Category A

NV16-31501A, research and development project

Name: Tkáňové inženýrství epitelů: Buňky a protokoly pro regenerativní medicínu

Citovat

SEDLÁKOVÁ, Veronika, Zbyněk VORÁČ, Josef JAROŠ, Radka KOPECKÁ, Michaela KLOUČKOVÁ, Michal SVOBODA, Libor STREIT, Jana DUMKOVÁ, Kateřina VAŠÍČKOVÁ, Milan ALBERTI and Aleš HAMPL. Enhanced bioactivity of electrospun PCL and PLLA scaffolds blended with amino-phosphazene. Materials Letters. Amsterdam: Elsevier Science, 2018, vol. 228, OCT 1 2018, p. 339-343. ISSN 0167-577X. Available from: https://dx.doi.org/10.1016/j.matlet.2018.06.023.

@article{1445536,
   author = {Sedláková, Veronika and Voráč, Zbyněk and Jaroš, Josef and Kopecká, Radka and Kloučková, Michaela and Svoboda, Michal and Streit, Libor and Dumková, Jana and Vašíčková, Kateřina and Alberti, Milan and Hampl, Aleš},
   article_location = {Amsterdam},
   article_number = {OCT 1 2018},
   doi = {http://dx.doi.org/10.1016/j.matlet.2018.06.023},
   keywords = {Phosphazene; Amino; Electrospinning; Biomaterials; Biomimetic; Morphology},
   language = {eng},
   issn = {0167-577X},
   journal = {Materials Letters},
   title = {Enhanced bioactivity of electrospun PCL and PLLA scaffolds blended with amino-phosphazene},
   url = {https://www.sciencedirect.com/science/article/pii/S0167577X18309297?via%3Dihub},
   volume = {228},
   year = {2018}
}

TY  - JOUR
ID  - 1445536
AU  - Sedláková, Veronika - Voráč, Zbyněk - Jaroš, Josef - Kopecká, Radka - Kloučková, Michaela - Svoboda, Michal - Streit, Libor - Dumková, Jana - Vašíčková, Kateřina - Alberti, Milan - Hampl, Aleš
PY  - 2018
TI  - Enhanced bioactivity of electrospun PCL and PLLA scaffolds blended with amino-phosphazene
JF  - Materials Letters
VL  - 228
IS  - OCT 1 2018
SP  - 339-343
EP  - 339-343
PB  - Elsevier Science
SN  - 0167577X
KW  - Phosphazene
KW  - Amino
KW  - Electrospinning
KW  - Biomaterials
KW  - Biomimetic
KW  - Morphology
UR  - https://www.sciencedirect.com/science/article/pii/S0167577X18309297?via%3Dihub
N2  - Here we report for the first time that blending hexaamino-cyclo-triphosphazene with either poly-epsilon-caprolactone or poly-L-lactic acid enables the generation of blended electrospun scaffolds with enhanced bioactivities. These hexaamino-cyclo-triphosphazene-modified fibers significantly promote cell adhesion, spreading, metabolism, and proliferation. In addition to that we also report more efficient hexaaminocyclo-triphosphazene synthesis with a higher yield and purity.
ER  -

SEDLÁKOVÁ, Veronika, Zbyněk VORÁČ, Josef JAROŠ, Radka KOPECKÁ, Michaela KLOUČKOVÁ, Michal SVOBODA, Libor STREIT, Jana DUMKOVÁ, Kateřina VAŠÍČKOVÁ, Milan ALBERTI and Aleš HAMPL. Enhanced bioactivity of electrospun PCL and PLLA scaffolds blended with amino-phosphazene. \textit{Materials Letters}. Amsterdam: Elsevier Science, 2018, vol.~228, OCT 1 2018, p.~339-343. ISSN~0167-577X. Available from: https://dx.doi.org/10.1016/j.matlet.2018.06.023.

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