Online solid-phase extraction liquid chromatography-mass
spectrometry of hair cortisol using a surrogate analyte

J 2019

Online solid-phase extraction liquid chromatography-mass spectrometry of hair cortisol using a surrogate analyte

KOSTOLANSKÁ, Katarína, Lucie NOVOTNÁ, Eva TÁBORSKÁ and Ondřej PEŠ

Basic information

Original name

Online solid-phase extraction liquid chromatography-mass spectrometry of hair cortisol using a surrogate analyte

Authors

KOSTOLANSKÁ, Katarína (703 Slovakia, belonging to the institution), Lucie NOVOTNÁ (203 Czech Republic, belonging to the institution), Eva TÁBORSKÁ (203 Czech Republic, belonging to the institution) and Ondřej PEŠ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Chemical Papers, Cham, SPRINGER INTERNATIONAL PUBLISHING AG, 2019, 0366-6352

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10609 Biochemical research methods

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 0.963 in 2017

RIV identification code

RIV/00216224:14110/19:00108893

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s11696-018-0560-1

UT WoS

000458121900014

Keywords in English

Endogenous cortisol; Long-term hair concentration; Surrogate analyte LC–MS; Online SPE

Abstract

V originále

Online SPE LC–MS with 13C3-cortisol as a surrogate analyte was developed, validated and applied for obtaining hair cortisol levels of 114 healthy volunteers. The first 3 cm from a posterior vertex position were analyzed as three individual segments resulting in 310 hair cortisol levels, which were used, after log transformation, to predict a range of values observed in future. The median value of hair cortisol was 4.76 pg/mg. The employed method allowed simple processing, high throughput and may be readily expanded to analyze additional steroid compounds in hair.

Links

MUNI/A/0910/2017, interní kód MU

Name: Studium molekulární podstaty vybraných patologických stavů a onemocnění (Acronym: stumopo)

Investor: Masaryk University, Category A

Citovat

KOSTOLANSKÁ, Katarína, Lucie NOVOTNÁ, Eva TÁBORSKÁ and Ondřej PEŠ. Online solid-phase extraction liquid chromatography-mass spectrometry of hair cortisol using a surrogate analyte. Chemical Papers. Cham: SPRINGER INTERNATIONAL PUBLISHING AG, 2019, vol. 73, No 1, p. 151-158. ISSN 0366-6352. Available from: https://dx.doi.org/10.1007/s11696-018-0560-1.

@article{1449218,
   author = {Kostolanská, Katarína and Novotná, Lucie and Táborská, Eva and Peš, Ondřej},
   article_location = {Cham},
   article_number = {1},
   doi = {http://dx.doi.org/10.1007/s11696-018-0560-1},
   keywords = {Endogenous cortisol; Long-term hair concentration; Surrogate analyte LC–MS; Online SPE},
   language = {eng},
   issn = {0366-6352},
   journal = {Chemical Papers},
   title = {Online solid-phase extraction liquid chromatography-mass spectrometry of hair cortisol using a surrogate analyte},
   url = {https://link.springer.com/article/10.1007/s11696-018-0560-1},
   volume = {73},
   year = {2019}
}

TY  - JOUR
ID  - 1449218
AU  - Kostolanská, Katarína - Novotná, Lucie - Táborská, Eva - Peš, Ondřej
PY  - 2019
TI  - Online solid-phase extraction liquid chromatography-mass spectrometry of hair cortisol using a surrogate analyte
JF  - Chemical Papers
VL  - 73
IS  - 1
SP  - 151-158
EP  - 151-158
PB  - SPRINGER INTERNATIONAL PUBLISHING AG
SN  - 03666352
KW  - Endogenous cortisol
KW  - Long-term hair concentration
KW  - Surrogate analyte LC–MS
KW  - Online SPE
UR  - https://link.springer.com/article/10.1007/s11696-018-0560-1
L2  - https://link.springer.com/article/10.1007/s11696-018-0560-1
N2  - Online SPE LC–MS with 13C3-cortisol as a surrogate analyte was developed, validated and applied for obtaining hair cortisol levels of 114 healthy volunteers. The first 3 cm from a posterior vertex position were analyzed as three individual segments resulting in 310 hair cortisol levels, which were used, after log transformation, to predict a range of values observed in future. The median value of hair cortisol was 4.76 pg/mg. The employed method allowed simple processing, high throughput and may be readily expanded to analyze additional steroid compounds in hair.
ER  -

KOSTOLANSKÁ, Katarína, Lucie NOVOTNÁ, Eva TÁBORSKÁ and Ondřej PEŠ. Online solid-phase extraction liquid chromatography-mass spectrometry of hair cortisol using a surrogate analyte. \textit{Chemical Papers}. Cham: SPRINGER INTERNATIONAL PUBLISHING AG, 2019, vol.~73, No~1, p.~151-158. ISSN~0366-6352. Available from: https://dx.doi.org/10.1007/s11696-018-0560-1.

Detailed Information on Publication Record