Lung cancer and socioeconomic status in a pooled analysis of
case-control studies

J 2018

Lung cancer and socioeconomic status in a pooled analysis of case-control studies

HOVANEC, Jan, Jack SIEMIATYCKI, David I. CONWAY, Ann OLSSON, Isabele STUCKER et. al.

Basic information

Original name

Lung cancer and socioeconomic status in a pooled analysis of case-control studies

Authors

HOVANEC, Jan (276 Germany), Jack SIEMIATYCKI (124 Canada), David I. CONWAY (826 United Kingdom of Great Britain and Northern Ireland), Ann OLSSON (250 France), Isabele STUCKER (250 France), Florence GUIDA (250 France), Karl-Heinz JOCKEL (276 Germany), Hermann POHLABELN (276 Germany), Wolfgang AHRENS (276 Germany), Irene BRUSKE (276 Germany), Heinz-Erich WICHMANN (276 Germany), Per GUSTAVSSON (752 Sweden), Dario CONSONNI (380 Italy), Franco MERLETTI (380 Italy), Lorenzo RICHIARDI (380 Italy), Lorenzo SIMONATO (380 Italy), Cristina FORTES (380 Italy), Marie-Elise PARENT (124 Canada), John MCLAUGHLIN (124 Canada), Paul DEMERS (124 Canada), Maria Teresa LANDI (840 United States of America), Neil CAPORASO (840 United States of America), Adonina TARDON (724 Spain), David ZARIDZE (643 Russian Federation), Neonila SZESZENIA-DABROWSKA (616 Poland), Peter RUDNAI (348 Hungary), Jolanta LISSOWSKA (616 Poland), Eleonora FABIANOVA (703 Slovakia), John FIELD (642 Romania), Rodica Stanescu DUMITRU (642 Romania), Vladimir BENCKO (203 Czech Republic), Lenka FORETOVÁ (203 Czech Republic, belonging to the institution), Vladimir JANOUT (203 Czech Republic), Hans KROMHOUT (528 Netherlands), Roel VERMEULEN (528 Netherlands), Paolo BOFFETTA (840 United States of America), Kurt STRAIF (250 France), Joachim SCHUZ (250 France), Benjamin KENDZIA (276 Germany), Beate PESCH (276 Germany), Thomas BRUNING (276 Germany) and Thomas BEHRENS (276 Germany, guarantor)

Edition

Plos one, San Francisco, Public Library Science, 2018, 1932-6203

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30204 Oncology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.776

RIV identification code

RIV/00216224:14110/18:00104082

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1371/journal.pone.0192999

UT WoS

000425554200042

Keywords in English

Lung cancer; socioeconomic status

Abstract

V originále

Background An association between low socioeconomic status (SES) and lung cancer has been observed in several studies, but often without adequate control for smoking behavior. We studied the association between lung cancer and occupationally derived SES, using data from the international pooled SYNERGY study. Methods Twelve case-control studies from Europe and Canada were included in the analysis. Based on occupational histories of study participants we measured SES using the International Socio-Economic Index of Occupational Status (ISEI) and the European Socio-economic Classification (ESeC). We divided the ISEI range into categories, using various criteria. Stratifying by gender, we calculated odds ratios (OR) and 95% confidence intervals (CI) by unconditional logistic regression, adjusting for age, study, and smoking behavior. We conducted analyses by histological subtypes of lung cancer and subgroup analyses by study region, birth cohort, education and occupational exposure to known lung carcinogens. Results The analysis dataset included 17,021 cases and 20,885 controls. There was a strong elevated OR between lung cancer and low SES, which was attenuated substantially after adjustment for smoking, however a social gradient persisted. SES differences in lung cancer risk were higher among men (lowest vs. highest SES category: ISEI OR 1.84 (95% CI 1.61-2.09); ESeC OR 1.53 (95% CI 1.44-1.63)), than among women (lowest vs. highest SES category: ISEI OR 1.54 (95% CI 1.20-1.98); ESeC OR 1.34 (95% CI 1.19-1.52)). Conclusion SES remained a risk factor for lung cancer after adjustment for smoking behavior.

Citovat

HOVANEC, Jan, Jack SIEMIATYCKI, David I. CONWAY, Ann OLSSON, Isabele STUCKER, Florence GUIDA, Karl-Heinz JOCKEL, Hermann POHLABELN, Wolfgang AHRENS, Irene BRUSKE, Heinz-Erich WICHMANN, Per GUSTAVSSON, Dario CONSONNI, Franco MERLETTI, Lorenzo RICHIARDI, Lorenzo SIMONATO, Cristina FORTES, Marie-Elise PARENT, John MCLAUGHLIN, Paul DEMERS, Maria Teresa LANDI, Neil CAPORASO, Adonina TARDON, David ZARIDZE, Neonila SZESZENIA-DABROWSKA, Peter RUDNAI, Jolanta LISSOWSKA, Eleonora FABIANOVA, John FIELD, Rodica Stanescu DUMITRU, Vladimir BENCKO, Lenka FORETOVÁ, Vladimir JANOUT, Hans KROMHOUT, Roel VERMEULEN, Paolo BOFFETTA, Kurt STRAIF, Joachim SCHUZ, Benjamin KENDZIA, Beate PESCH, Thomas BRUNING and Thomas BEHRENS. Lung cancer and socioeconomic status in a pooled analysis of case-control studies. Plos one. San Francisco: Public Library Science, 2018, vol. 13, No 2, p. 1-18. ISSN 1932-6203. Available from: https://dx.doi.org/10.1371/journal.pone.0192999.

@article{1451356,
   author = {Hovanec, Jan and Siemiatycki, Jack and Conway, David I. and Olsson, Ann and Stucker, Isabele and Guida, Florence and Jockel, KarlandHeinz and Pohlabeln, Hermann and Ahrens, Wolfgang and Bruske, Irene and Wichmann, HeinzandErich and Gustavsson, Per and Consonni, Dario and Merletti, Franco and Richiardi, Lorenzo and Simonato, Lorenzo and Fortes, Cristina and Parent, MarieandElise and McLaughlin, John and Demers, Paul and Landi, Maria Teresa and Caporaso, Neil and Tardon, Adonina and Zaridze, David and SzeszeniaandDabrowska, Neonila and Rudnai, Peter and Lissowska, Jolanta and Fabianova, Eleonora and Field, John and Dumitru, Rodica Stanescu and Bencko, Vladimir and Foretová, Lenka and Janout, Vladimir and Kromhout, Hans and Vermeulen, Roel and Boffetta, Paolo and Straif, Kurt and Schuz, Joachim and Kendzia, Benjamin and Pesch, Beate and Bruning, Thomas and Behrens, Thomas},
   article_location = {San Francisco},
   article_number = {2},
   doi = {http://dx.doi.org/10.1371/journal.pone.0192999},
   keywords = {Lung cancer; socioeconomic status},
   language = {eng},
   issn = {1932-6203},
   journal = {Plos one},
   title = {Lung cancer and socioeconomic status in a pooled analysis of case-control studies},
   volume = {13},
   year = {2018}
}

TY  - JOUR
ID  - 1451356
AU  - Hovanec, Jan - Siemiatycki, Jack - Conway, David I. - Olsson, Ann - Stucker, Isabele - Guida, Florence - Jockel, Karl-Heinz - Pohlabeln, Hermann - Ahrens, Wolfgang - Bruske, Irene - Wichmann, Heinz-Erich - Gustavsson, Per - Consonni, Dario - Merletti, Franco - Richiardi, Lorenzo - Simonato, Lorenzo - Fortes, Cristina - Parent, Marie-Elise - McLaughlin, John - Demers, Paul - Landi, Maria Teresa - Caporaso, Neil - Tardon, Adonina - Zaridze, David - Szeszenia-Dabrowska, Neonila - Rudnai, Peter - Lissowska, Jolanta - Fabianova, Eleonora - Field, John - Dumitru, Rodica Stanescu - Bencko, Vladimir - Foretová, Lenka - Janout, Vladimir - Kromhout, Hans - Vermeulen, Roel - Boffetta, Paolo - Straif, Kurt - Schuz, Joachim - Kendzia, Benjamin - Pesch, Beate - Bruning, Thomas - Behrens, Thomas
PY  - 2018
TI  - Lung cancer and socioeconomic status in a pooled analysis of case-control studies
JF  - Plos one
VL  - 13
IS  - 2
SP  - 1-18
EP  - 1-18
PB  - Public Library Science
SN  - 19326203
KW  - Lung cancer
KW  - socioeconomic status
N2  - Background An association between low socioeconomic status (SES) and lung cancer has been observed in several studies, but often without adequate control for smoking behavior. We studied the association between lung cancer and occupationally derived SES, using data from the international pooled SYNERGY study. Methods Twelve case-control studies from Europe and Canada were included in the analysis. Based on occupational histories of study participants we measured SES using the International Socio-Economic Index of Occupational Status (ISEI) and the European Socio-economic Classification (ESeC). We divided the ISEI range into categories, using various criteria. Stratifying by gender, we calculated odds ratios (OR) and 95% confidence intervals (CI) by unconditional logistic regression, adjusting for age, study, and smoking behavior. We conducted analyses by histological subtypes of lung cancer and subgroup analyses by study region, birth cohort, education and occupational exposure to known lung carcinogens. Results The analysis dataset included 17,021 cases and 20,885 controls. There was a strong elevated OR between lung cancer and low SES, which was attenuated substantially after adjustment for smoking, however a social gradient persisted. SES differences in lung cancer risk were higher among men (lowest vs. highest SES category: ISEI OR 1.84 (95% CI 1.61-2.09); ESeC OR 1.53 (95% CI 1.44-1.63)), than among women (lowest vs. highest SES category: ISEI OR 1.54 (95% CI 1.20-1.98); ESeC OR 1.34 (95% CI 1.19-1.52)). Conclusion SES remained a risk factor for lung cancer after adjustment for smoking behavior.
ER  -

HOVANEC, Jan, Jack SIEMIATYCKI, David I. CONWAY, Ann OLSSON, Isabele STUCKER, Florence GUIDA, Karl-Heinz JOCKEL, Hermann POHLABELN, Wolfgang AHRENS, Irene BRUSKE, Heinz-Erich WICHMANN, Per GUSTAVSSON, Dario CONSONNI, Franco MERLETTI, Lorenzo RICHIARDI, Lorenzo SIMONATO, Cristina FORTES, Marie-Elise PARENT, John MCLAUGHLIN, Paul DEMERS, Maria Teresa LANDI, Neil CAPORASO, Adonina TARDON, David ZARIDZE, Neonila SZESZENIA-DABROWSKA, Peter RUDNAI, Jolanta LISSOWSKA, Eleonora FABIANOVA, John FIELD, Rodica Stanescu DUMITRU, Vladimir BENCKO, Lenka FORETOVÁ, Vladimir JANOUT, Hans KROMHOUT, Roel VERMEULEN, Paolo BOFFETTA, Kurt STRAIF, Joachim SCHUZ, Benjamin KENDZIA, Beate PESCH, Thomas BRUNING and Thomas BEHRENS. Lung cancer and socioeconomic status in a pooled analysis of case-control studies. \textit{Plos one}. San Francisco: Public Library Science, 2018, vol.~13, No~2, p.~1-18. ISSN~1932-6203. Available from: https://dx.doi.org/10.1371/journal.pone.0192999.

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