J 2018

The optimal bowel preparation intervals before colonoscopy: A randomized study comparing polyethylene glycol and low-volume solutions

KOJECKY, Vladimir, Jan MATOUS, Radan KEIL, Milan DASTYCH, Zdena ZADOROVA et. al.

Basic information

Original name

The optimal bowel preparation intervals before colonoscopy: A randomized study comparing polyethylene glycol and low-volume solutions

Authors

KOJECKY, Vladimir (203 Czech Republic), Jan MATOUS (203 Czech Republic), Radan KEIL (203 Czech Republic), Milan DASTYCH (203 Czech Republic, belonging to the institution), Zdena ZADOROVA (203 Czech Republic), Michal VARGA (203 Czech Republic), Radek KROUPA (203 Czech Republic, belonging to the institution), Jiří DOLINA (203 Czech Republic, guarantor, belonging to the institution), Miroslav MISUREC (203 Czech Republic), Aleš HEP (203 Czech Republic, belonging to the institution) and Martin GRIVA (203 Czech Republic)

Edition

DIGESTIVE AND LIVER DISEASE, NEW YORK, ELSEVIER SCIENCE INC, 2018, 1590-8658

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30219 Gastroenterology and hepatology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.037

RIV identification code

RIV/00216224:14110/18:00104089

Organization unit

Faculty of Medicine

UT WoS

000428631100009

Keywords in English

Ascorbic acid; Bowel preparation; Colonoscopy; Polyethylene glycol; Sodium picosulfate

Tags

Tags

International impact, Reviewed
Změněno: 11/2/2019 14:15, Soňa Böhmová

Abstract

V originále

Background & aims: The optimal duration of bowel preparation has only been assessed for polyethylene glycol (PEG). The aim of the study was to determine the intervals for achieving a satisfactory quality/tolerability of the preparation using PEG/ascorbic acid (PEGA) and sodium picosulphate/magnesium citrate (SPMC), and to compare them with 4L of PEG. Methods: A randomized, endoscopist-blinded, multicentre study. The 612 outpatients referred to a colonoscopy, were prepared using PEG, SPMC, PEGA. The quality, tolerability, duration of the preparation, and the interval from the end of the preparation to the colonoscopy was assessed. Results: Optimum duration of the preparation was similar for both PEG and SPMC (>= 7.3 vs. >= 8.8 h, overall >= 8.4 h). Optimum interval to the colonoscopy was <= 11.8 h and did not differ between preparations (PEG, PEGA <= 11.8, SPMC <= 13.3 h). These times were the only predictors for a satisfactory preparation. The tolerability depends on the product type (SPMC) only. Timing of the preparation or the other factors had no impact on tolerability. Conclusion: The optimum intervals for bowel preparation are identical for all preparations. Satisfactory preparation is achived at the preparation length >= 8.4 h and the time to colonoscopy <= 11.8 h.