Treatment of infrapopliteal post-PTA dissection with tack
implants: 12-month results from the TOBA-BTK study

J 2018

Treatment of infrapopliteal post-PTA dissection with tack implants: 12-month results from the TOBA-BTK study

BRODMANN, Marianne, Christian WISSGOTT, Andrew HOLDEN, Robert STAFFA, Thomas ZELLER et. al.

Basic information

Original name

Treatment of infrapopliteal post-PTA dissection with tack implants: 12-month results from the TOBA-BTK study

Authors

BRODMANN, Marianne (40 Austria, guarantor), Christian WISSGOTT (276 Germany), Andrew HOLDEN (554 New Zealand), Robert STAFFA (203 Czech Republic, belonging to the institution), Thomas ZELLER (276 Germany), Thodur VASUDEVAN (554 New Zealand) and Peter SCHNEIDER (840 United States of America)

Edition

Catheterization and Cardiovascular Interventions, Hoboken, Wiley-Blackwell, 2018, 1522-1946

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 2.551

RIV identification code

RIV/00216224:14110/18:00104168

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1002/ccd.27568

UT WoS

000440646400023

Keywords in English

balloon angioplasty; critical limb ischemia; dissection; infrapopliteal arteries; peripheral artery disease; tibial artery

Abstract

V originále

Objectives: The Tack implant is designed for focal, minimal metal management of dissections. This study evaluated Tacks for treating postpercutaneous transluminal angioplasty (PTA) dissection in patients with below-the-knee (BTK) arterial occlusive disease. Background: PTA is the most commonly used endovascular treatment for patients with occlusive disease of the BTK vessels. Post-PTA dissection is a significant clinical problem that results in poor outcomes, but currently there are limited treatment options for managing dissections. Methods: This prospective, single-arm study evaluated patients with CLI and BTK lesions; 11.4% were Rutherford category (RC) 4 and 88.6% were RC 5. BTK occlusive disease was treated with standard PTA and post-PTA dissections were treated with Tack placement. The primary safety endpoint was a composite of major adverse limb events (MALE) and perioperative death (POD) at 30 days. Other endpoints included: device success; procedure success (vessel patency in the absence of MALE); freedom from clinically driven target lesion revascularization (CD-TLR); primary patency; and changes in RC. Data through 12 months are presented. Results: Thirty-two of 35 (91.4%) patients had post-PTA dissection and successful deployment of Tacks. Procedural success was achieved in 34/35 (97.1%) patients with no MALEs at 30 days. The 12-month patency rate was 78.4% by vessel, 77.4% by patient, and freedom from CD-TLR was 93.5%. Significant (P < .0001) improvement from baseline was observed in RC (75% of patients improved 4 or 5 steps). Conclusion: Tack implant treatment of post-PTA dissection was safe and effective for treatment of BTK dissections and resulted in reasonable 12-month patency and low rates of CD-TLR.

Citovat

BRODMANN, Marianne, Christian WISSGOTT, Andrew HOLDEN, Robert STAFFA, Thomas ZELLER, Thodur VASUDEVAN and Peter SCHNEIDER. Treatment of infrapopliteal post-PTA dissection with tack implants: 12-month results from the TOBA-BTK study. Catheterization and Cardiovascular Interventions. Hoboken: Wiley-Blackwell, 2018, vol. 92, No 1, p. 96-105. ISSN 1522-1946. Available from: https://dx.doi.org/10.1002/ccd.27568.

@article{1454556,
   author = {Brodmann, Marianne and Wissgott, Christian and Holden, Andrew and Staffa, Robert and Zeller, Thomas and Vasudevan, Thodur and Schneider, Peter},
   article_location = {Hoboken},
   article_number = {1},
   doi = {http://dx.doi.org/10.1002/ccd.27568},
   keywords = {balloon angioplasty; critical limb ischemia; dissection; infrapopliteal arteries; peripheral artery disease; tibial artery},
   language = {eng},
   issn = {1522-1946},
   journal = {Catheterization and Cardiovascular Interventions},
   title = {Treatment of infrapopliteal post-PTA dissection with tack implants: 12-month results from the TOBA-BTK study},
   volume = {92},
   year = {2018}
}

TY  - JOUR
ID  - 1454556
AU  - Brodmann, Marianne - Wissgott, Christian - Holden, Andrew - Staffa, Robert - Zeller, Thomas - Vasudevan, Thodur - Schneider, Peter
PY  - 2018
TI  - Treatment of infrapopliteal post-PTA dissection with tack implants: 12-month results from the TOBA-BTK study
JF  - Catheterization and Cardiovascular Interventions
VL  - 92
IS  - 1
SP  - 96-105
EP  - 96-105
PB  - Wiley-Blackwell
SN  - 15221946
KW  - balloon angioplasty
KW  - critical limb ischemia
KW  - dissection
KW  - infrapopliteal arteries
KW  - peripheral artery disease
KW  - tibial artery
N2  - Objectives: The Tack implant is designed for focal, minimal metal management of dissections. This study evaluated Tacks for treating postpercutaneous transluminal angioplasty (PTA) dissection in patients with below-the-knee (BTK) arterial occlusive disease. Background: PTA is the most commonly used endovascular treatment for patients with occlusive disease of the BTK vessels. Post-PTA dissection is a significant clinical problem that results in poor outcomes, but currently there are limited treatment options for managing dissections. Methods: This prospective, single-arm study evaluated patients with CLI and BTK lesions; 11.4% were Rutherford category (RC) 4 and 88.6% were RC 5. BTK occlusive disease was treated with standard PTA and post-PTA dissections were treated with Tack placement. The primary safety endpoint was a composite of major adverse limb events (MALE) and perioperative death (POD) at 30 days. Other endpoints included: device success; procedure success (vessel patency in the absence of MALE); freedom from clinically driven target lesion revascularization (CD-TLR); primary patency; and changes in RC. Data through 12 months are presented. Results: Thirty-two of 35 (91.4%) patients had post-PTA dissection and successful deployment of Tacks. Procedural success was achieved in 34/35 (97.1%) patients with no MALEs at 30 days. The 12-month patency rate was 78.4% by vessel, 77.4% by patient, and freedom from CD-TLR was 93.5%. Significant (P < .0001) improvement from baseline was observed in RC (75% of patients improved 4 or 5 steps). Conclusion: Tack implant treatment of post-PTA dissection was safe and effective for treatment of BTK dissections and resulted in reasonable 12-month patency and low rates of CD-TLR.
ER  -

BRODMANN, Marianne, Christian WISSGOTT, Andrew HOLDEN, Robert STAFFA, Thomas ZELLER, Thodur VASUDEVAN and Peter SCHNEIDER. Treatment of infrapopliteal post-PTA dissection with tack implants: 12-month results from the TOBA-BTK study. \textit{Catheterization and Cardiovascular Interventions}. Hoboken: Wiley-Blackwell, 2018, vol.~92, No~1, p.~96-105. ISSN~1522-1946. Available from: https://dx.doi.org/10.1002/ccd.27568.

Detailed Information on Publication Record