JAVANAINEN, Tuija, Heli TOLPPANEN, Johan LASSUS, Markku S. NIEMINEN, Alessandro SIONIS, Jindřich ŠPINAR, Jose SILVA-CARDOSO, Matias LINDHOLM, Marek BANASZEWSKI, Veli-Pekka HARJOLA and Raija JURKKO. Predictive value of the baseline electrocardiogram ST-segment pattern in cardiogenic shock: Results from the CardShock Study. ANNALS OF NONINVASIVE ELECTROCARDIOLOGY. HOBOKEN: WILEY, 2018, vol. 23, No 5, p. 1-9. ISSN 1082-720X. Available from: https://dx.doi.org/10.1111/anec.12561.
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Basic information
Original name Predictive value of the baseline electrocardiogram ST-segment pattern in cardiogenic shock: Results from the CardShock Study
Authors JAVANAINEN, Tuija (246 Finland, guarantor), Heli TOLPPANEN (246 Finland), Johan LASSUS (246 Finland), Markku S. NIEMINEN (246 Finland), Alessandro SIONIS (724 Spain), Jindřich ŠPINAR (203 Czech Republic, belonging to the institution), Jose SILVA-CARDOSO (620 Portugal), Matias LINDHOLM (208 Denmark), Marek BANASZEWSKI (616 Poland), Veli-Pekka HARJOLA (246 Finland) and Raija JURKKO (246 Finland).
Edition ANNALS OF NONINVASIVE ELECTROCARDIOLOGY, HOBOKEN, WILEY, 2018, 1082-720X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.235
RIV identification code RIV/00216224:14110/18:00104203
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1111/anec.12561
UT WoS 000443676200010
Keywords in English acute coronary syndrome; acute heart failure; cardiogenic shock; electrocardiography; prognosis
Tags 14110211, rivok
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 10/2/2019 17:45.
Abstract
BackgroundThe most common aetiology of cardiogenic shock (CS) is acute coronary syndrome (ACS), but even up to 20%-50% of CS is caused by other disorders. ST-segment deviations in the electrocardiogram (ECG) have been investigated in patients with ACS-related CS, but not in those with other CS aetiologies. We set out to explore the prevalence of different ST-segment patterns and their associations with the CS aetiology, clinical findings and 90-day mortality. MethodsWe analysed the baseline ECG of 196 patients who were included in a multinational prospective study of CS. The patients were divided into 3 groups: (a) ST-segment elevation (STE). (b) ST-segment depression (STDEP). (c) No ST-segment deviation or ST-segment impossible to analyse (NSTD). A subgroup analysis of the ACS patients was conducted. ResultsST-segment deviations were present in 80% of the patients: 52% had STE and 29% had STDEP. STE was associated with the ACS aetiology, but one-fourth of the STDEP patients had aetiology other than ACS. The overall 90-day mortality was 41%: in STE 47%, STDEP 36% and NSTD 33%. In the multivariate mortality analysis, only STE predicted mortality (HR 1.74, CI95 1.07-2.84). In the ACS subgroup, the patients were equally effectively revascularized, and no differences in the survival were noted between the study groups. ConclusionST-segment elevation is associated with the ACS aetiology and high mortality in the unselected CS population. If STE is not present, other aetiologies must be considered. When effectively revascularized, the prognosis is similar regardless of the ST-segment pattern in ACS-related CS.
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