VÁCLAVÍK, Daniel, Michal BAR, Lukáš KLEČKA, David HOLEŠ, Martin ČÁBAL and Robert MIKULÍK. Prehospital stroke scale (FAST PLUS Test) predicts patients with intracranial large vessel occlusion. Brain and Behavior. Hoboken: John Wiley and Sons Inc., 2018, vol. 8, No 9, p. 1-7. ISSN 2162-3279. Available from: https://dx.doi.org/10.1002/brb3.1087.
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Basic information
Original name Prehospital stroke scale (FAST PLUS Test) predicts patients with intracranial large vessel occlusion
Authors VÁCLAVÍK, Daniel (203 Czech Republic), Michal BAR (203 Czech Republic, guarantor), Lukáš KLEČKA (203 Czech Republic), David HOLEŠ (203 Czech Republic), Martin ČÁBAL (203 Czech Republic) and Robert MIKULÍK (203 Czech Republic, belonging to the institution).
Edition Brain and Behavior, Hoboken, John Wiley and Sons Inc. 2018, 2162-3279.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30103 Neurosciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.072
RIV identification code RIV/00216224:14110/18:00104208
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1002/brb3.1087
UT WoS 000445850000019
Keywords in English large vessel occlusion stroke; paramedics; triage test
Tags 14110127, rivok
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 10/2/2019 17:47.
Abstract
Background and Purpose: Mechanical thrombectomy (MT) is indicated for the treatment of large vessel occlusion (LVO) stroke. MT should be provided as quickly as possible; therefore, a test identifying suspected LVO in the prehospitalization stage is needed to ensure direct transport to a comprehensive stroke center (CSC). We assume that patients with clinically severe hemiparesis have a high probability of LVO stroke. We modified the FAST test into the FAST PLUS test: The first part is the FAST test and the second part evaluates the presence of severe arm or leg motor deficit. This prospective multicenter study evaluates the specificity and sensitivity of the FAST PLUS test in detecting LVO stroke. Methods: Paramedics were trained through e-learning to conduct the FAST PLUS test. All prehospital suspected stroke patients who were administered the FAST PLUS test were included. Demographics, National Institutes of Health Stroke Scale (NIHSS) score, brain computed tomography (CT), and CT angiography (CTA) were recorded. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and receiver operating curve (ROC) area for LVO were calculated. Results: The study included 435 patients. LVO were found in 124 patients (28%). Sensitivity was 93%, specificity was 47%, PPV was 41%, NPV was 94%, and ROC area for ICA/MCA occlusion was 0.65. Intracerebral hemorrhage (ICH) was identified in 48 patients (11%). Conclusion: We found that the FAST PLUS test had a high sensitivity for LVO stroke. Of the 435 patients, 41% were all directly transported to a CSC based on positive FAST PLUS test scores and were potential candidates for MT.
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